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1. WO2013006401 - METHODS AND COMPOSITIONS OF PROTEIN ANTIGENS FOR THE DIAGNOSIS AND TREATMENT OF HERPES SIMPLEX VIRUSES TYPE 1 AND 2

Publication Number WO/2013/006401
Publication Date 10.01.2013
International Application No. PCT/US2012/044814
International Filing Date 29.06.2012
IPC
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 31/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
A61P 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
CPC
A61K 2039/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
70Multivalent vaccine
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
A61K 39/245
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
C12N 2710/16633
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16611Simplexvirus, e.g. human herpesvirus 1, 2
16633Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
Applicants
  • IMMPORT THERAPEUTICS, INC. [US]/[US] (AllExceptUS)
  • DAVIES, David Huw [GB]/[US] (UsOnly)
  • LIANG, Xiaowu [US]/[US] (UsOnly)
  • FELGNER, Philip [US]/[US] (UsOnly)
Inventors
  • DAVIES, David Huw
  • LIANG, Xiaowu
  • FELGNER, Philip
Agents
  • FESSENMAIER, Martin
Priority Data
61/503,79001.07.2011US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS OF PROTEIN ANTIGENS FOR THE DIAGNOSIS AND TREATMENT OF HERPES SIMPLEX VIRUSES TYPE 1 AND 2
(FR) MÉTHODES ET COMPOSITIONS D'ANTIGÈNES PROTÉIQUES POUR LE DIAGNOSTIC ET LE TRAITEMENT DES VIRUS DE L'HERPES SIMPLEX DE TYPE 1 ET 2
Abstract
(EN)
Contemplated compositions, devices, and methods are drawn to various antigens from Herpes Simplex Virus type 1 (HSV-1) and Herpes Simplex Virus type 2 (HSV-2) and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
(FR)
L'invention concerne des compositions, des dispositifs et des méthodes relatives à divers antigènes du virus de l'Herpex Simplex de type 1 (VHS-1) et du virus de l'Herpex Simplex de type 2 (VHS-2), ainsi que leurs utilisations dans des vaccins, des agents thérapeutiques et divers tests diagnostiques. Dans des aspects particulièrement préférés, les antigènes sont immunodominants et possèdent des réactivités relatives connues et quantifiées par rapport aux sera d'une population infectée par ledit pathogène, et/ou possèdent une association connue à un paramètre de maladie.
Latest bibliographic data on file with the International Bureau