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1. WO2013006312 - REAGENT STORAGE ON A DROPLET ACTUATOR

Publication Number WO/2013/006312
Publication Date 10.01.2013
International Application No. PCT/US2012/044235
International Filing Date 26.06.2012
IPC
G01N 27/403 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
403Cells and electrode assemblies
G01N 33/48 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 35/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
CPC
B01L 2200/0678
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0678Facilitating or initiating evaporation
B01L 2200/16
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
16Reagents, handling or storing thereof
B01L 2300/0816
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
B01L 2400/0427
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0403specific forces
0415electrical forces, e.g. electrokinetic
0427Electrowetting
B01L 3/502784
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502769characterised by multiphase flow arrangements
502784specially adapted for droplet or plug flow, e.g. digital microfluidics
B01L 3/502792
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502769characterised by multiphase flow arrangements
502784specially adapted for droplet or plug flow, e.g. digital microfluidics
502792for moving individual droplets on a plate, e.g. by locally altering surface tension
Applicants
  • ADVANCED LIQUID LOGIC INC [US]/[US] (AllExceptUS)
  • FOLEY, Jennifer [US]/[US] (UsOnly)
  • BURDE, Stefan [US]/[US] (UsOnly)
Inventors
  • FOLEY, Jennifer
  • BURDE, Stefan
Agents
  • MILLS, Eric
Priority Data
61/504,79306.07.2011US
61/507,86314.07.2011US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) REAGENT STORAGE ON A DROPLET ACTUATOR
(FR) STOCKAGE DE RÉACTIFS SUR UN ACTIONNEUR DE MANIPULATION DE GOUTTELETTES
Abstract
(EN)
A method of providing a droplet comprising one or more reagents, the method comprising, depositing a first aqueous droplet comprising the one or more reagents on a surface; drying the droplet to yield a dried composition on the surface comprising the one or more reagents; covering the dried composition with oil; and causing a second aqueous droplet in the oil to contact the dried composition and thereby resuspend one or more reagents.
(FR)
La présente invention concerne un procédé pour fournir une gouttelette comprenant un ou plusieurs réactifs, le procédé consistant à déposer une première gouttelette aqueuse comprenant le ou les réactifs, sur une surface, à sécher la gouttelette pour obtenir une composition sèche sur la surface, comprenant le ou les réactifs, à recouvrir la composition obtenue d'huile, et à faire entrer en contact une seconde gouttelette aqueuse dans l'huile avec la composition sèche et ainsi remettre en suspension le ou les réactifs.
Latest bibliographic data on file with the International Bureau