Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2013006278) IDENTITY ELUCIDATION OF UNKNOWN METABOLITES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2013/006278 International Application No.: PCT/US2012/043461
Publication Date: 10.01.2013 International Filing Date: 21.06.2012
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
METABOLON, INC. [US/US]; 617 Davis Drive, Suite 400 Durham, NC 27713, US (AllExceptUS)
HELMHOLTZ ZENTRUM MUENCHEN [DE/DE]; Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH) Ingoldstaedter Landstrasse 1 85764 Neuherberg, DE (AllExceptUS)
MILBURN, Michael [US/US]; US (UsOnly)
KASTENMUELLER, Gabriele [DE/DE]; DE (UsOnly)
KRUMSIEK, Jan [DE/DE]; DE (UsOnly)
SUHRE, Karsten [DE/QA]; QA (UsOnly)
Inventors:
MILBURN, Michael; US
KASTENMUELLER, Gabriele; DE
KRUMSIEK, Jan; DE
SUHRE, Karsten; QA
Agent:
RHODES, Allyn, B.; Brinks Hofer Gilson & Lione P.O. Box 110285 Research Triangle Park, NC 27709, US
Priority Data:
61/503,67301.07.2011US
Title (EN) IDENTITY ELUCIDATION OF UNKNOWN METABOLITES
(FR) ELUCIDATION DE L'IDENTITE DE METABOLITES INCONNUS
Abstract:
(EN) A method of elucidating the identity of an unknown metabolite comprising measuring amounts of known and unknown metabolites in subjects; associating the unknown metabolite with a specific gene from a gene association study; determining a protein associated with the specific gene and analyzing information for the protein; associating the unknown metabolite with concentrations and/or ratios of other metabolites in subjects; obtaining chemical structural data for the unknown metabolite; and using the information obtained to elucidate the identity of the unknown metabolite.
(FR) Méthode d'élucidation de l'identité d'un métabolite inconnu comprenant la mesure des quantités des métabolites connus et inconnus chez des patients, l'association du métabolite inconnu avec un gène spécifique à partir d'une étude d'association de gène, la détermination d'une protéine associée avec le gène spécifique et l'analyse des informations concernant la protéine, l'associant du métabolite inconnu avec des concentrations et/ou des proportions d'autres métabolites chez des patients et l'utilisation des informations obtenues pour élucider l'identité du métabolite inconnu.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2726636US20140212872