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1. (WO2013001507) TREATMENT PLANNING BASED ON POLYPEPTIDE RADIOTOXICITY SERUM MARKERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2013/001507 International Application No.: PCT/IB2012/053323
Publication Date: 03.01.2013 International Filing Date: 29.06.2012
IPC:
A61N 5/10 (2006.01) ,G01N 33/574 (2006.01) ,G01N 33/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
N
ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5
Radiation therapy
10
X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
KONINKLIJKE PHILIPS N.V. [NL/NL]; High Tech Campus 5 NL-5656 AE Eindhoven, NL (AllExceptUS)
BITTER, Katrin [DE/NL]; NL (UsOnly)
RIBBING, Carolina [SE/DE]; NL (UsOnly)
Inventors:
BITTER, Katrin; NL
RIBBING, Carolina; NL
Agent:
VAN VELZEN, Maaike; High Tech Campus, Building 44 NL-5600 AE Eindhoven, NL
Priority Data:
61/502,96030.06.2011US
Title (EN) TREATMENT PLANNING BASED ON POLYPEPTIDE RADIOTOXICITY SERUM MARKERS
(FR) SCHÉMA THÉRAPEUTIQUE REPOSANT SUR DES MARQUEURS SÉRIQUES DE RADIOTOXICITÉ POLYPEPTIDIQUES
Abstract:
(EN) A method includes at least one of creating or adapting a treatment plan for a patient based on a set of serum polypeptides of the patient that are indicative of a radiotoxicity of the patient at least one of before or after at least one of a plurality of radiotherapy treatments of the treatment plan, wherein the radiotoxicity is induced by radiation exposure from the radiotherapy treatment. A system includes a treatment planning device (108) that facilitates at least one of creating or adapting a treatment plan for a patient based on amounts or concentrations of a set of serum polypeptides of the patient that indicate a high risk of or an early radiotoxicity of the patient to radiation from radiotherapy.
(FR) La présente invention concerne un procédé comprenant la création ou l'adaptation d'un schéma thérapeutique pour un patient en fonction d'un ensemble de polypeptides sériques du patient qui sont des marqueurs d'une radiotoxicité chez le patient, avant et/ou après au moins l'un des traitements d'une pluralité de traitement de radiothérapie, la radiotoxicité étant induite par l'exposition à un rayonnement lors d'un traitement de radiothérapie. Un système comprend un dispositif d'établissement de schéma thérapeutique (108) qui facilite la création et/ou l'adaptation d'un schéma thérapeutique pour un patient en fonction de quantités ou de concentrations d'un ensemble de polypeptides sériques du patient qui indiquent un risque élevé ou une radiotoxicité précoce chez le patient exposé au rayonnement au cours d'une radiothérapie.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CN103648585US20140113388