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1. (WO2012177367) ABSORBANCE SPECTRUM SCANNING FLOW CYTOMETRY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/177367 International Application No.: PCT/US2012/040126
Publication Date: 27.12.2012 International Filing Date: 31.05.2012
IPC:
G01N 21/64 (2006.01) ,G01N 15/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
64
Fluorescence; Phosphorescence
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15
Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
Applicants:
BECTON, DICKINSON AND COMPANY [US/US]; 1 Becton Drive Franklin Lakes, New Jersey 07417, US (AllExceptUS)
NORTON, Pierce, O. [US/US]; US (UsOnly)
CHEN, Yong, Qin [US/US]; US (UsOnly)
Inventors:
NORTON, Pierce, O.; US
CHEN, Yong, Qin; US
Agent:
MILES, Kirk, M.; The Webb Law Firm One Gateway Center 420 Fort Duquesne Boulevard, Suite 1200 Pittsburgh, Pennsylvania 15222, US
Priority Data:
61/500,70724.06.2011US
61/557,33408.11.2011US
Title (EN) ABSORBANCE SPECTRUM SCANNING FLOW CYTOMETRY
(FR) CYTOMÉTRIE DE FLUX À BALAYAGE DE SPECTRE D'ABSORBANCE
Abstract:
(EN) The present invention provides systems and methods for analyzing the excitation spectra of fluorescent particles in a flowing stream. The system uses a white light laser and color separation optics to provide a spatially-distributed, continuous color-spectrum excitation light system that is used to illuminate a region of a flowing stream. A particle that passes through the detection region traverses the full dispersed spectrum of excitation light, and the fluorescence emissions from the particle are continuously measured as it passes through the detection region. The measured fluorescence emissions at each wavelength of excitation light, which changes through full spectrum of the excitation light as the particle passes through the detection region, provides the excitation spectrum of the particle.
(FR) La présente invention concerne des systèmes et des procédés destinés à analyser les spectres d'excitation de particules fluorescentes dans un courant circulant. Le système utilise un laser de lumière blanche et des optiques de séparation de couleur pour fournir un système de lumière d'excitation de spectre de couleur distribué spatialement, continu qui est utilisé pour éclairer une région d'un courant circulant. Une particule qui passe à travers la région de détection traverse le spectre totalement dispersé de lumière d'excitation et les émissions de fluorescence de la particule sont mesurées en continu à mesure qu'elle passe à travers la région de détection. Les émissions de fluorescence mesurées à chaque longueur d'onde de la lumière d'excitation, qui changent à travers un spectre total de la lumière d'excitation à mesure que la particule passe à travers la région de détection, fournissent le spectre d'excitation de la particule.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2724146US20140093949