Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2012174477) HIGH THROUGH-PUT SCREENING IN SKIN FIBROBLASTS WITH AN ALPHA-SYNUCLEIN TRIPLICATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/174477 International Application No.: PCT/US2012/042815
Publication Date: 20.12.2012 International Filing Date: 15.06.2012
IPC:
C12N 5/071 (2010.01) ,G01N 33/50 (2006.01) ,C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
THE PARKINSON'S INSTITUTE [US/US]; 675 Almanor Avenue Sunnyvale, CA 94085, US (AllExceptUS)
MAK, Sally [US/US]; US (UsOnly)
SCHUELE, Birgitt [DE/US]; US (UsOnly)
LANGSTON, William, J. [US/US]; US (UsOnly)
Inventors:
MAK, Sally; US
SCHUELE, Birgitt; US
LANGSTON, William, J.; US
Agent:
WILLIS, Mmichael, A.; Wilson Sonsini Goodrich & Rosati 650 Page Mill Road Palo Alto, CA 94304-1050, US
Priority Data:
61/497,61716.06.2011US
Title (EN) HIGH THROUGH-PUT SCREENING IN SKIN FIBROBLASTS WITH AN ALPHA-SYNUCLEIN TRIPLICATION
(FR) CRIBLAGE À HAUT DÉBIT DANS DES FIBROBLASTES DE LA PEAU AVEC UNE TRIPLICATION DE L'ALPHA-SYNUCLÉINE
Abstract:
(EN) Human-derived fibroblast cells with copy number variation for alpha-synuclein, and methods of use thereof, are provided. For example, compositions and methods for high through-put screening of potential therapies for neurodegenerative disease such as Parkinson's disease are provided.
(FR) L'invention concerne des cellules de fibroblastes dérivées d'êtres humains avec une variation du nombre de copies pour l'alpha-synucléine, et les procédés d'utilisation de celles-ci. Par exemple, l'invention concerne des compositions et des procédés pour le criblage à haut débit de thérapies potentielles pour une maladie neurodégénérative comme la maladie de Parkinson.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2721145US20150037257