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1. (WO2012171035) CARBOHYDRATE-BASED COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/171035 International Application No.: PCT/US2012/041962
Publication Date: 13.12.2012 International Filing Date: 11.06.2012
IPC:
C08F 293/00 (2006.01) ,A61L 27/00 (2006.01)
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
293
Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
Applicants:
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION [US/US]; 4311 11th Avenue NE, Suite 500 Seattle, WA 98105-4608, US (AllExceptUS)
STAYTON, Patrick, S. [US/US]; US (UsOnly)
MANGANIELLO, Matthew [US/US]; US (UsOnly)
CONVERTINE, Anthony [US/US]; US (UsOnly)
RATNER, Daniel, M. [US/US]; US (UsOnly)
CHOW, Yu-Hua [US/US]; US (UsOnly)
SONG, Eun-Ho [US/US]; US (UsOnly)
GHOSN, Bilal [US/US]; US (UsOnly)
SCHNAPP, Lynn [US/US]; US (UsOnly)
KELLER, Salka [DE/US]; US (UsOnly)
ROY, Debashish [BD/US]; US (UsOnly)
Inventors:
STAYTON, Patrick, S.; US
MANGANIELLO, Matthew; US
CONVERTINE, Anthony; US
RATNER, Daniel, M.; US
CHOW, Yu-Hua; US
SONG, Eun-Ho; US
GHOSN, Bilal; US
SCHNAPP, Lynn; US
KELLER, Salka; US
ROY, Debashish; US
Agent:
LAWSON, L., Rhys; Christensen O'connor Johnson Kindness PLLC 1420 Fifth Avenue, Suite 2800 Seattle, WA 98101, US
Priority Data:
61/495,90810.06.2011US
61/495,91510.06.2011US
61/495,92210.06.2011US
Title (EN) CARBOHYDRATE-BASED COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY
(FR) COMPOSITIONS À BASE DE GLUCIDES ET PROCÉDÉS POUR LA DÉLIVRANCE CIBLÉE DE MÉDICAMENTS
Abstract:
(EN) Provided herein are compositions and methods for intracellular delivery. The compositions are polymer compositions in which the polymer serves as a carrier for therapeutic and/or diagnostic agents. The polymer compositions are effective in targeted delivery of therapeutic and/or diagnostic agents to a cell. The polymer compositions include a targeting moiety that includes carbohydrate groups that effectively target specific cell surface receptors. The polymer compositions also include an agent binding moiety that effectively associates the therapeutic and/or diagnostic agent to be delivered to the cell.
(FR) L'invention concerne des compositions et des procédés pour la délivrance intracellulaire. Les compositions sont des compositions de polymère dans lesquelles le polymère sert de support pour des agents thérapeutiques et/ou diagnostiques. Les compositions de polymère sont efficaces dans la délivrance ciblée d'agents thérapeutiques et/ou diagnostiques à une cellule. Les compositions de polymère incluent une partie ciblante qui inclut des groupes de glucide qui ciblent efficacement des récepteurs spécifiques de la surface cellulaire. Les compositions de polymère incluent aussi une partie de liaison à l'agent qui associe efficacement l'agent thérapeutique et/ou diagnostique à délivrer à la cellule.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20140235790