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1. (WO2012166705) SUPRAMOLECULAR NANOFIBERS AND HYDROGELS BASED ON AMINO ACID-NUCLEOBASE-GLYCOSIDE CONJUGATES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/166705 International Application No.: PCT/US2012/039821
Publication Date: 06.12.2012 International Filing Date: 29.05.2012
IPC:
C07H 17/02 (2006.01) ,C07H 19/00 (2006.01) ,A61K 38/14 (2006.01) ,A61K 31/706 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
17
Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
02
Heterocyclic radicals containing only nitrogen as ring hetero atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19
Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
14
Peptides containing saccharide radicals; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7042
Compounds having saccharide radicals and heterocyclic rings
7052
having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706
containing six-membered rings with nitrogen as a ring hetero atom
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
BRANDEIS UNIVERSITY [US/US]; 415 South Street Waltham, MA 02453-2728, US (AllExceptUS)
XU, Bing [CN/US]; US (UsOnly)
Inventors:
XU, Bing; US
Agent:
GORDON, Dana, M.; Foley Hoag LLP Patent Group 155 Seaport Boulevard Boston, MA 02210-2600, US
Priority Data:
61/491,54431.05.2011US
Title (EN) SUPRAMOLECULAR NANOFIBERS AND HYDROGELS BASED ON AMINO ACID-NUCLEOBASE-GLYCOSIDE CONJUGATES
(FR) NANOFIBRES ET HYDROGELS SUPRAMOLÉCULAIRES À BASE DE CONJUGUÉS ACIDE AMINÉ-NUCLÉOBASE-GLUCOSIDE
Abstract:
(EN) Described herein are hydrogelators that include a nucleobase, an amino acid, and a glycoside. The hydrogelators have increased resistance to proteases and can self-assemble into supramolecular nanofibers or hydrogels. The supramolecular structures may be used to help grow cells or deliver a substance to a cell.
(FR) L'invention concerne des promoteurs d'hydrogel qui comportent une nucléobase, un acide aminé et un glucoside. Ces promoteurs d'hydrogel présentent une résistance accrue aux protéases et peuvent former par auto-assemblage des nanofibres ou des hydrogels supramoléculaires. Ces structures supramoléculaires peuvent être utilisées pour favoriser la croissance de cellules ou pour délivrer une substance à une cellule.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)