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1. WO2012136250 - HMGB1 SPECIFIC MONOCLONAL ANTIBODIES

Publication Number WO/2012/136250
Publication Date 11.10.2012
International Application No. PCT/EP2011/055274
International Filing Date 05.04.2011
IPC
C07K 16/24 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
24against cytokines, lymphokines or interferons
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Applicants
  • DIA.PRO DIAGNOSTIC BIOPROBES S.R.L. [IT]/[IT] (AllExceptUS)
  • SCOZZESI, Cristina [IT]/[IT] (UsOnly)
Inventors
  • SCOZZESI, Cristina
Agents
  • ZACCARO, Elisabetta
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HMGB1 SPECIFIC MONOCLONAL ANTIBODIES
(FR) ANTICORPS MONOCLONAUX SPÉCIFIQUES DE HMGB1
Abstract
(EN)
The present invention concerns monoclonal antibodies specifically binding the human HMGB1 protein and further HMGB1 proteins of mammalian origin and also concerns fragments thereof, nucleic acids encoding such antibodies or fragments thereof, as well as vectors, cells, and compositions comprising the antibodies or nucleic acids, and uses thereof.
(FR)
La présente invention concerne des anticorps monoclonaux se liant spécifiquement à la protéine HMGB1 humaine, ainsi qu'à des protéines HMGB1 d'origine mammifère, et concerne également des fragments de ceux-ci, des acides nucléiques codant pour de tels anticorps ou des fragments de ceux-ci, ainsi que des vecteurs, des cellules et des compositions comportant les anticorps ou les acides nucléiques. L'invention concerne en outre leurs utilisations.
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