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1. (WO2012128902) CHANGES IN THE EXPRESSION OF MIR-200C/141 CLUSTER OF MICRORNAS AS BIOMARKERS FOR EPITHELIAL-TO-MESENCHYMAL TRANSITION IN HUMAN COLORECTAL CANCER METASTASIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/128902    International Application No.:    PCT/US2012/027131
Publication Date: 27.09.2012 International Filing Date: 29.02.2012
IPC:
C12Q 1/68 (2006.01)
Applicants: BAYLOR RESEARCH INSTITUTE [US/US]; 3310 Live Oak Street Suite 501 Dallas, TX 75204 (US) (For All Designated States Except US).
GOEL, Ajay [US/US]; (US) (For US Only).
BOLAND, C., Richard [US/US]; (US) (For US Only).
HUR, Keun [KR/US]; (US) (For US Only)
Inventors: GOEL, Ajay; (US).
BOLAND, C., Richard; (US).
HUR, Keun; (US)
Agent: SHISHIMA, Gina, N.; Fulbright & Jaworski LLP 98 San Jacinto Blvd., Suite 1100 Austin, TX 78701-4255 (US)
Priority Data:
61/454,053 18.03.2011 US
Title (EN) CHANGES IN THE EXPRESSION OF MIR-200C/141 CLUSTER OF MICRORNAS AS BIOMARKERS FOR EPITHELIAL-TO-MESENCHYMAL TRANSITION IN HUMAN COLORECTAL CANCER METASTASIS
(FR) CHANGEMENT DANS L'EXPRESSION DU GROUPE DE MICROARN MIR-200C/141 COMME MARQUEURS BIOLOGIQUES D'UNE TRANSITION ÉPITHÉLIO-MÉSENCHYMATEUSE DANS UNE MÉTASTASE DE CANCER COLORECTAL HUMAIN
Abstract: front page image
(EN)The present invention includes methods, kits and biomarkers for detecting and determining the development of colorectal cancer (CRC) metastasis based on changes in the expression pattern of one or more microRNAs (miR) or miR clusters that include the miR-200/141 family.
(FR)La présente invention concerne des procédés, des kits et des marqueurs biologiques permettant de détecter et de déterminer le développement d'une métastase de cancer colorectal (CCR) d'après des changements dans le profil d'expression d'un ou de plusieurs microARN (miR) ou groupes de miR qui comprennent la famille miR-200/141.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)