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1. (WO2012126531) METHOD FOR DIAGNOSING ACUTE CORONARY SYNDROME (ACS)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/126531    International Application No.:    PCT/EP2011/054567
Publication Date: 27.09.2012 International Filing Date: 24.03.2011
IPC:
G01N 33/68 (2006.01)
Applicants: CAVADIS B.V. [NL/NL]; Catharijnesingel 52 NL-3511 GC Utrecht (NL) (For All Designated States Except US).
DE KLEIJN, Dominique [NL/NL]; (NL) (For US Only).
PASTERKAMP, Gerard [NL/NL]; (NL) (For US Only).
TIMMERS, Leonardus [NL/NL]; (NL) (For US Only).
SZE, Siu Kwan [SG/SG]; (SG) (For US Only)
Inventors: DE KLEIJN, Dominique; (NL).
PASTERKAMP, Gerard; (NL).
TIMMERS, Leonardus; (NL).
SZE, Siu Kwan; (SG)
Agent: VAN SOMEREN, Petronella Francisca Hendrika Maria; Sweelinckplein 1 NL-2517 GK Den Haag (NL)
Priority Data:
Title (EN) METHOD FOR DIAGNOSING ACUTE CORONARY SYNDROME (ACS)
(FR) MÉTHODE DE DIAGNOSTIC DU SYNDROME CORONAIRE AIGU (SCA)
Abstract: front page image
(EN)The invention relates to a method of diagnosing the occurrence of acute coronary syndrome in a subject, comprising determining the presence of a biomarker that is indicative of the occurrence of acute coronary syndrome in an exosome sample from the subject. The exosome sample consists of exosomes that are isolated from a body fluid, a body fluid that comprises exosomes selected from serum, plasma, blood, urine, amniotic fluid, malignant ascites, bronchoalveolar lavage fluid, synovial fluid, breast milk, saliva, in particular serum.
(FR)L'invention concerne une méthode de diagnostic de la survenue d'un syndrome coronaire aigu chez un sujet, comprenant une étape consistant à déterminer la présence d'un biomarqueur révélateur de la survenue d'un syndrome coronaire aigu dans un échantillon d'exosomes prélevé chez le sujet. Ledit échantillon d'exosomes est constitué d'exosomes isolés à partir d'un liquide organique, ledit liquide organique contenant des exosomes et étant choisi parmi le sérum, le plasma, le sang, l'urine, le liquide amniotique, les ascites malignes, le liquide de lavage broncho-alvéolaire, le liquide synovial, le lait de femme, la salive et, tout particulièrement, le sérum.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)