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1. (WO2012125603) MACROCYCLIC COMPOUNDS AS ALK, FAK AND JAK2 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/125603    International Application No.:    PCT/US2012/028856
Publication Date: 20.09.2012 International Filing Date: 13.03.2012
IPC:
C07D 487/08 (2006.01)
Applicants: CEPHALON, INC. [US/US]; 41 Moores Road P.O. Box 4011 Frazer, Pennsylvania 19355 (US) (For All Designated States Except US).
BRESLIN, Henry J. [US/US]; (US) (For US Only).
DORSEY, Bruce [US/US]; (US) (For US Only).
OTT, Gregory R. [US/US]; (US) (For US Only)
Inventors: BRESLIN, Henry J.; (US).
DORSEY, Bruce; (US).
OTT, Gregory R.; (US)
Agent: DARKES, Paul R.; Cephalon, Inc. 41 Moores Road Frazer, Pennsylvania 19355 (US)
Priority Data:
61/453,259 16.03.2011 US
Title (EN) MACROCYCLIC COMPOUNDS AS ALK, FAK AND JAK2 INHIBITORS
(FR) COMPOSÉS MACROCYLCIQUES COMME INHIBITEURS D'ALK, DE FAK ET DE JAK2
Abstract: front page image
(EN)The present invention provides compounds of Formula I or a pharmaceutically acceptable salt forms thereof, wherein R1, R2, R3, R4, R5, A and X are as defined herein, methods of treatment and uses thereof.
(FR)L'invention se réfère à des composés représentés par la formule I ou à des formes salines pharmaceutiquement acceptables de ceux-ci, R1, R2, R3, R4, R5, A et X étant tels que définis dans la demande, à des méthodes de traitement et à des utilisations de ces composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)