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1. (WO2012123971) A METHOD OF SCREENING ANTI-TUBERCULAR COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/123971    International Application No.:    PCT/IN2012/000184
Publication Date: 20.09.2012 International Filing Date: 16.03.2012
IPC:
G01N 33/68 (2006.01)
Applicants: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH [IN/IN]; Anusandhan Bhawan, Rafi Marg New Delhi 110001 (IN) (For All Designated States Except US).
SARKAR, Dhiman [IN/IN]; (IN) (For US Only).
SARKAR, Sampa [IN/IN]; (IN) (For US Only)
Inventors: SARKAR, Dhiman; (IN).
SARKAR, Sampa; (IN)
Agent: DHAWAN, Ramesh, Chander; Lall Lahiri & Salhotra Plot No. B-28 Sector 32 Institutional Area Gurgaon 122001 (IN)
Priority Data:
0737/DEL/2011 16.03.2011 IN
Title (EN) A METHOD OF SCREENING ANTI-TUBERCULAR COMPOUNDS
(FR) PROCÉDÉ DE CRIBLAGE DE COMPOSÉS ANTI-TUBERCULEUX
Abstract: front page image
(EN)Novel targets for screening anti tubercular targets and methods to use those targets to screen potential drugs for anti tubercular therapy are addressed through this invention. A method of screening anti-tubercular compounds that affect the binding between GroEL2 protein or a fragment thereof and a kit for screening of antitubercular drug candidates having an isolated gro EL 2 protein; Mts- Atf-Biotin Label Transfer Reagents and a culture medium comprising M. bovis BCG (ATCC 35745), M. smegmatis (ATCC 607) are disclosed.
(FR)L'invention concerne de nouvelles cibles pour le criblage d'agents anti-tuberculeux ainsi que des procédés d'utilisation de ces cibles pour cribler des médicaments potentiels pour le traitement de la tuberculose. L'invention concerne également un procédé de criblage de composés anti-tuberculeux qui affectent la liaison de la protéine GroEL2 ou d'un fragment de cette protéine, ainsi qu'une trousse de criblage de candidats-médicaments anti-tuberculeux qui comprend une protéine GroEL2 isolée, des réactifs de transfert marqueurs Mts-Atf-biotine et un milieu de culture comprenant M. bovis BCG (ATCC 35745), M. smegmatis (ATCC 607).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)