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1. (WO2012123294) APEX1 AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/123294    International Application No.:    PCT/EP2012/053839
Publication Date: 20.09.2012 International Filing Date: 07.03.2012
IPC:
G01N 33/68 (2006.01)
Applicants: ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Straße 116 68305 Mannheim (DE) (DE only).
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacher Strasse 124 CH-4070 Basel (CH) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
HAGMANN, Marie-Luise [DE/DE]; (DE) (For US Only).
KARL, Johann [DE/DE]; (DE) (For US Only).
RIEDLINGER, Julia [DE/DE]; (DE) (For US Only)
Inventors: HAGMANN, Marie-Luise; (DE).
KARL, Johann; (DE).
RIEDLINGER, Julia; (DE)
Agent: NASER, Werner; Roche Diagnostics GmbH P.O. Box 11 52 Nonnenwald 2 82372 Penzberg (DE)
Priority Data:
11157922.3 11.03.2011 EP
Title (EN) APEX1 AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
(FR) APEX1 EN TANT QUE MARQUEUR DE MALADIE PULMONAIRE OBSTRUCTIVE CHRONIQUE (COPD)
Abstract: front page image
(EN)The present invention relates to an in vitro method aiding in the assessment of chronic obstructive pulmonary disease (= COPD). It discloses the use of the protein APEX1 as a marker of COPD. Furthermore, it especially relates to a method for assessing COPD from a sample, derived from an individual by measuring the protein APEX1 in said sample in vitro.
(FR)La présente invention concerne un procédé in vitro aidant à l'évaluation de la maladie pulmonaire obstructive chronique (= COPD). L'invention concerne l'utilisation de la protéine APEX1 en tant que marqueur de COPD. En outre, l'invention concerne en particulier un procédé d'évaluation de la COPD à partir d'un échantillon issu d'un individu par la mesure de la protéine APEX1 dans ledit échantillon in vitro.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)