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1. WO2012122513 - GENERATION OF ANTI-FN14 MONOCLONAL ANTIBODIES BY EX-VIVO ACCELERATED ANTIBODY EVOLUTION

Publication Number WO/2012/122513
Publication Date 13.09.2012
International Application No. PCT/US2012/028584
International Filing Date 09.03.2012
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
C07K 16/28 (2006.01)
A61K 39/395 (2006.01)
A61P 35/00 (2006.01)
CPC
C07K 16/2878
C07K 16/30
C07K 2317/14
C07K 2317/23
C07K 2317/24
C07K 2317/56
Applicants
  • OMEROS CORPORATION [US/US]; 201 Elliott Avenue West Suite 500 Seattle, Washington 98119, US (AllExceptUS)
  • LEPPARD, John, Benjamin [US/US]; US (UsOnly)
  • WOOD, Christi, L. [US/US]; US (UsOnly)
  • CUMMINGS, W., Jason [US/US]; US (UsOnly)
  • YABUKI, Munehisa [JP/US]; US (UsOnly)
  • MAIZELS, Nancy [US/US]; US (UsOnly)
  • ALLISON, Daniel, S. [US/US]; US (UsOnly)
  • TJOELKER, Larry, W. [US/US]; US (UsOnly)
Inventors
  • LEPPARD, John, Benjamin; US
  • WOOD, Christi, L.; US
  • CUMMINGS, W., Jason; US
  • YABUKI, Munehisa; US
  • MAIZELS, Nancy; US
  • ALLISON, Daniel, S.; US
  • TJOELKER, Larry, W.; US
Agents
  • KELBON, Marcia, S.; Omeros Corporation 201 Elliott Avenue West Suite 500 Seattle, Washington 98119, US
Priority Data
61/451,47710.03.2011US
61/512,23627.07.2011US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GENERATION OF ANTI-FN14 MONOCLONAL ANTIBODIES BY EX-VIVO ACCELERATED ANTIBODY EVOLUTION
(FR) GÉNÉRATION D'ANTICORPS MONOCLONAUX ANTI-FN14 PAR DÉVELOPPEMENT ACCÉLÉRÉ D'ANTICORPS EX-VIVO
Abstract
(EN)
The present invention relates generally to anti-FN14 antibodies. In particular, the anti-FN14 antibodies described herein are useful for the treatment of diseases, such as a variety of cancers, associated with expression of FN14.
(FR)
La présente invention concerne de manière générale les anticorps anti-FN14. En particulier, les anticorps anti-FN14 décrits dans le présent document sont utiles pour le traitement de maladies, telles qu'une diversité de cancers en relation avec l'expression du FN14.
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