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1. (WO2012122378) ANTIBODY-LIKE PROTEINS FOR THERAPEUTIC AND DIAGNOSTIC USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/122378    International Application No.:    PCT/US2012/028286
Publication Date: 13.09.2012 International Filing Date: 08.03.2012
IPC:
C12P 21/02 (2006.01), C07K 16/28 (2006.01), A61K 38/16 (2006.01), C12N 15/13 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street Suite 200 Philadelphia, PA 19104 (US) (For All Designated States Except US).
GREENE, Mark, I. [US/US]; (US) (For US Only).
ZHANG, Hongtao [US/US]; (US) (For US Only)
Inventors: GREENE, Mark, I.; (US).
ZHANG, Hongtao; (US)
Agent: CALDWELL, John, W.; Woodcock Washburn LLP Cira Centre, 12th Floor 2929 Arch Street Philadelphia, PA 19104-2891 (US)
Priority Data:
61/450,435 08.03.2011 US
Title (EN) ANTIBODY-LIKE PROTEINS FOR THERAPEUTIC AND DIAGNOSTIC USE
(FR) PROTÉINES DE TYPE ANTICORPS POUR USAGE THÉRAPEUTIQUE ET DIAGNOSTIC
Abstract: front page image
(EN)Disclosed herein are recombinant protein scaffolds for use in producing antigen-binding proteins. Related antigen-binding proteins are also provided herein. In addition, nucleic acids encoding such recombinant protein scaffolds and antigen-binding proteins are also described. Vectors and cells useful for expression of the described proteins are also provided, as are methods of use.
(FR)La présente invention concerne des échafaudages de protéines recombinantes destinés à être utilisés dans la production de protéines de liaison à l'antigène. L'invention porte en outre sur des protéines de liaison à l'antigène afférentes. En outre, l'invention a trait à des acides nucléiques codant pour ces échafaudages de protéines recombinantes et ces protéines de liaison à l'antigène. L'invention porte par ailleurs sur des vecteurs et des cellules utiles dans l'expression des protéines décrites, ainsi que sur des procédés d'utilisation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)