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1. (WO2012121862) VALPROIC ACID DERIVATIVE COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2012/121862 International Application No.: PCT/US2012/025627
Publication Date: 13.09.2012 International Filing Date: 17.02.2012
IPC:
C07C 69/003 (2006.01) ,C08B 37/02 (2006.01) ,C07H 15/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
02
Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
03
esterified with alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
B
POLYSACCHARIDES; DERIVATIVES THEREOF
37
Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
02
Dextran; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15
Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
02
Acyclic radicals, not substituted by cyclic structures
04
attached to an oxygen atom of a saccharide radical
Applicants: HASSAN, A. M. Mahbub[US/US]; US (UsOnly)
HOCHHAUS, Guenther[DE/US]; US (UsOnly)
CARNEY, Paul, R.[US/US]; US (UsOnly)
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION[US/US]; P.o.box 115575 Gainesville, FL 32611-5575, US (AllExceptUS)
Inventors: HASSAN, A. M. Mahbub; US
HOCHHAUS, Guenther; US
CARNEY, Paul, R.; US
Agent: CORLESS, Peter, F.; Edwards Wildman Palmer LLP P.O.Box 55874 Boston, MA 02205, US
Priority Data:
61/444,00917.02.2011US
Title (EN) VALPROIC ACID DERIVATIVE COMPOUNDS
(FR) COMPOSÉS DÉRIVÉS DE L'ACIDE VALPROÏQUE
Abstract:
(EN) The invention relates to valproic acid:dextran compounds and methods of using them. The invention further relates to pharmaceutical compositions and methods for treating a variety of diseases and disorders, including brain trauma, epilepsy, seizures and ocular diseases, disorders or symptoms thereof.
(FR) L'invention concerne des composés acide valproïque:dextran et des procédés pour les utiliser. L'invention concerne en outre des compositions pharmaceutiques et des procédés de traitement de diverses maladies et troubles, notamment un trauma cérébral, l'épilepsie, des crises épileptiques et des maladies oculaires et leurs troubles ou leurs symptômes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)