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Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/119979    International Application No.:    PCT/EP2012/053732
Publication Date: 13.09.2012 International Filing Date: 05.03.2012
C07D 487/04 (2006.01), A61K 31/519 (2006.01), A61P 3/00 (2006.01), A61P 9/00 (2006.01), A61P 35/00 (2006.01)
Applicants: GLAXOSMITHKLINE LLC [US/US]; One Franklin Plaza 200 North 16th Street Philadelphia, Pennsylvania 19102 (US) (For All Designated States Except US).
BOUILLOT, Anne Marie Jeanne [FR/FR]; (FR) (For US Only).
DAUGAN, Alain Claude-Marie [FR/FR]; (FR) (For US Only).
LAMOTTE, Yann [FR/FR]; (FR) (For US Only).
MIRGUET, Olivier [FR/FR]; (FR) (For US Only)
Inventors: BOUILLOT, Anne Marie Jeanne; (FR).
DAUGAN, Alain Claude-Marie; (FR).
LAMOTTE, Yann; (FR).
MIRGUET, Olivier; (FR)
Agent: HILLIER, Mark; GlaxoSmithKline Global Patents CN925.1 980 Great West Road Brentford Middlesex TW8 9GS (GB)
Priority Data:
61/449,857 07.03.2011 US
Abstract: front page image
(EN)The present invention relates to pyrimidinedione compounds of formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds of formula (I) or salts thereof as activators of AMPK.
(FR)La présente invention concerne des pyrimidinediones de formule (I), leurs sels, des compositions pharmaceutiques les incluant et leur utilisation en médecine. En particulier, la présente invention concerne des composés de formule (I) ou leurs sels en tant qu'activateurs d'AMPK.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)