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1. (WO2012118903) SCLEROSTIN AND DKK-1 BISPECIFIC BINDING AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2012/118903 International Application No.: PCT/US2012/027154
Publication Date: 07.09.2012 International Filing Date: 29.02.2012
IPC:
C07K 16/22 (2006.01) ,C07K 16/18 (2006.01) ,A61K 39/395 (2006.01) ,A61P 19/08 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
22
against growth factors
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
08
for bone diseases, e.g. rachitism, Paget's disease
Applicants: FLORIO, Monica[US/US]; US (UsOnly)
ARORA, Taruna[US/US]; US (UsOnly)
PASZTY, Christopher, J., R.[US/US]; US (UsOnly)
RICHARDS, William, G.[US/US]; US (UsOnly)
AMGEN INC.[US/US]; One Amgen Center Drive Thousand Oaks, CA 91320-1799, US (AllExceptUS)
Inventors: FLORIO, Monica; US
ARORA, Taruna; US
PASZTY, Christopher, J., R.; US
RICHARDS, William, G.; US
Agent: BRASHEAR, Jeanne, M.; Marshall, Gerstein & Borun LLP 233 S. Wacker Drive Chicago, IL 60606-6357, US
Priority Data:
61/448,08901.03.2011US
61/482,97905.05.2011US
Title (EN) SCLEROSTIN AND DKK-1 BISPECIFIC BINDING AGENTS
(FR) AGENTS LIANTS BISPÉCIFIQUES
Abstract:
(EN) The invention relates to bispecific anti-sclerostin/anti-DKK1 binding agents and combinations of anti-sclerostin and anti-DKK1 binding agents, and related methods of treatment.
(FR) La présente invention se rapporte à des agents liants bispécifiques anti-sclérostine/anti-DKK1. L'invention se rapporte d'autre part à des combinaisons d'agents liants anti-sclérostine et anti-DKK1. L'invention se rapporte par ailleurs à des méthodes de traitement associées.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)