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Machine translation
1. (WO2012118717) COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVE HIGH EFFICIENCY GENE DISRUPTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/118717    International Application No.:    PCT/US2012/026653
Publication Date: 07.09.2012 International Filing Date: 24.02.2012
IPC:
C12N 9/00 (2006.01), C12N 15/09 (2006.01), C12N 15/00 (2006.01)
Applicants: SEATTLE CHILDREN'S RESEARCH INSTITUTE [US/US]; M/s Cw8-4, P.o. Box 5371 Seattle, WA 98145-5005 (US) (For All Designated States Except US).
SCHARENBERG, Andrew, M. [US/US]; (US) (For US Only).
CERTO, Michael, T. [US/US]; (US) (For US Only).
GWIAZDA, Kamila, Sabina [CA/US]; (US) (For US Only)
Inventors: SCHARENBERG, Andrew, M.; (US).
CERTO, Michael, T.; (US).
GWIAZDA, Kamila, Sabina; (US)
Agent: FURMAN, Eric, S.; Knobbe Martens Olson & Bear Llp 2040 Main Street, Fourteenth Floor Irvine, CA 92614 (US)
Priority Data:
61/447,672 28.02.2011 US
Title (EN) COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVE HIGH EFFICIENCY GENE DISRUPTION
(FR) COUPLAGE D'ENDONUCLÉASES AVEC DES ENZYMES DE TRAITEMENT DES EXTRÉMITÉS FAVORISANT LA DISRUPTION GÉNIQUE À HAUT RENDEMENT
Abstract: front page image
(EN)The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the polynucleotide ends generated by endonuclease cleavage.
(FR)La présente invention concerne la co-expression d'une endonucléase et d'une enzyme de traitement des extrémités dans le but d'améliorer le traitement des extrémités de polynucléotides produites par le clivage avec une endonucléase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)