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Pub. No.:    WO/2012/117323    International Application No.:    PCT/IB2012/050876
Publication Date: 07.09.2012 International Filing Date: 27.02.2012
A61K 39/00 (2006.01), A61P 35/00 (2006.01)
Applicants: CADILA PHARMACEUTICALS LIMITED [IN/IN]; "Cadila Corporate Campus", Sarkhej - Dholka Road, Bhat, Ahmedabad, Gujarat 382210 (IN) (For All Designated States Except US).
KHAMAR, Bakulesh Mafatlal [IN/IN]; (IN) (For US Only).
DESAI, Nirav Manojkumar [IN/IN]; (IN) (For US Only).
SHUKLA, Chandreshwar Prasad [IN/IN]; (IN) (For US Only).
DARJI, Avani Devenbhai [IN/IN]; (IN) (For US Only).
MODI, Indravadan Ambalal [IN/IN]; (IN) (For US Only)
Inventors: KHAMAR, Bakulesh Mafatlal; (IN).
DESAI, Nirav Manojkumar; (IN).
SHUKLA, Chandreshwar Prasad; (IN).
DARJI, Avani Devenbhai; (IN).
MODI, Indravadan Ambalal; (IN)
KHAMAR, Bakulesh Mafatlal; Cadila Pharmaceuticals Limited, "Cadila Corporate campus" Sarkhej - Dholka Road, Bhat Ahmedabad, Gujarat 382210 (IN)
Priority Data:
555/MUM/2011 28.02.2011 IN
Abstract: front page image
(EN)The present invention relates to vaccine(s) comprising cancer cells expressing antigen(s), excipients, optionally adjuvant wherein the said antigen(s) is expressed on contacting the said cancer cell with p38 inducer, for use in treatment of Cancer. The vaccine composition induces specific immune response against homologous and heterologus cancer cells of the tissue /organ. The invention also provides method of preparing the same.
(FR)La présente invention concerne un (des) vaccin(s) comprenant des cellules cancéreuses exprimant un ou plusieurs antigènes, des excipients, facultativement un adjuvant, ledit ou lesdits antigènes étant exprimés lors de la mise en contact de ladite cellule cancéreuse avec un inducteur de p38, destinés à être utilisés dans traitement du cancer. La composition vaccinale induit une réponse immunitaire spécifique contre des cellules cancéreuses homologues et hétérologues du tissu/de l'organe. L'invention concerne en outre un procédé de préparation associé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)