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1. (WO2012117097) BIARYL DERIVATIVES AS SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/117097    International Application No.:    PCT/EP2012/053653
Publication Date: 07.09.2012 International Filing Date: 02.03.2012
IPC:
C07D 333/40 (2006.01), C07C 233/00 (2006.01), A61K 31/381 (2006.01), A61P 19/10 (2006.01)
Applicants: UNIVERSITÄT DES SAARLANDES [DE/DE]; Campus Saarbrücken 66123 Saarbrücken (DE) (For All Designated States Except US).
HARTMANN, Rolf [DE/DE]; (DE) (For US Only).
MARCHAIS-OBERWINKLER, Sandrine [FR/DE]; (DE) (For US Only).
XU, Kuiying [CN/DE]; (DE) (For US Only).
WERTH, Ruth [DE/DE]; (DE) (For US Only)
Inventors: HARTMANN, Rolf; (DE).
MARCHAIS-OBERWINKLER, Sandrine; (DE).
XU, Kuiying; (DE).
WERTH, Ruth; (DE)
Agent: VON KREISLER SELTING WERNER; Deichmannhaus am Dom Bahnhofsvorplatz 1 50667 Köln (DE)
Priority Data:
11156733.5 03.03.2011 EP
Title (EN) BIARYL DERIVATIVES AS SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 INHIBITORS
(FR) DÉRIVÉS BIARYLE EN TANT QU'INHIBITEURS SÉLECTIFS DE LA 17BÊTA-HYDROXYSTÉROÏDE DÉSHYDROGÉNASE DE TYPE 2
Abstract: front page image
(EN)The invention relates to selective, non-steroidal 17beta-hydroxysteroid dehydrogenase type 2 (17beta-HSD2) inhibitors of formula (I), their production and use, notably for the treatment and prophylaxis of sex steroid deficient diseases like osteoporosis in men and women.
(FR)L'invention concerne des inhibiteurs sélectifs, non stéroïdes, de la 17bêta-hydroxystéroïde déshydrogénase de type 2 (17bêta-HSD2) de formule (I), leur production et leur utilisation, notamment pour le traitement et la prophylaxie de maladies de carence en stéroïdes sexuels, telles que l'ostéoporose chez les hommes et les femmes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)