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1. (WO2012117059) PHARMACEUTICALLY ACTIVE DISUBSTITUTED PYRIDINE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/117059    International Application No.:    PCT/EP2012/053517
Publication Date: 07.09.2012 International Filing Date: 01.03.2012
IPC:
C07D 213/74 (2006.01), A61K 31/44 (2006.01), A61P 35/00 (2006.01)
Applicants: LEAD DISCOVERY CENTER GMBH [DE/DE]; Otto-Hahn-Str. 15 44227 Dortmund (DE) (For All Designated States Except US).
BAYER INTELLECTUAL PROPERTY GMBH [DE/DE]; Alfred-Nobel-Strasse 10 40789 Monheim (DE) (For All Designated States Except US).
RÜHTER, Gerd [DE/DE]; (DE) (For US Only).
NUSSBAUMER, Peter [AT/DE]; (DE) (For US Only).
CHOIDAS, Axel [DE/DE]; (DE) (For US Only).
SCHULTZ-FADEMRECHT, Carsten [DE/DE]; (DE) (For US Only).
KLEBL, Bert [DE/DE]; (DE) (For US Only).
EICKHOFF, Jan [DE/DE]; (DE) (For US Only)
Inventors: RÜHTER, Gerd; (DE).
NUSSBAUMER, Peter; (DE).
CHOIDAS, Axel; (DE).
SCHULTZ-FADEMRECHT, Carsten; (DE).
KLEBL, Bert; (DE).
EICKHOFF, Jan; (DE)
Agent: ARTH, Hans-Lothar; c/o ABK Patent Attorneys Jasminweg 9 14052 Berlin (DE)
Priority Data:
11075038.7 02.03.2011 EP
Title (EN) PHARMACEUTICALLY ACTIVE DISUBSTITUTED PYRIDINE DERIVATIVES
(FR) DÉRIVÉS DE PYRIDINE DISUBSTITUÉS PHARMACEUTIQUEMENT ACTIFS
Abstract: front page image
(EN)The present invention relates to disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted pyridine derivatives as inhibitors for a protein kinase.
(FR)La présente invention porte sur des dérivés de pyridine disubstitués et/ou des sels pharmaceutiquement acceptables de ceux-ci, sur l'utilisation de ces dérivés comme agents pharmaceutiquement actifs, en particulier pour la prophylaxie et/ou le traitement de maladies infectieuses, dont les maladies opportunistes, les maladies immunologiques, les maladies auto-immunes, les maladies cardiovasculaires, les maladies prolifératives des cellules, une inflammation, un dysfonctionnement érectile et l'accident vasculaire cérébral, et sur des compositions pharmaceutiques contenant au moins l'un desdits dérivés de pyridine disubstitués et/ou sels pharmaceutiquement acceptables de ceux-ci. En outre, la présente invention porte sur l'utilisation desdits dérivés de pyridine disubstitués comme inhibiteurs pour une protéine kinase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)