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Machine translation
1. (WO2012117000) 3-AMINO-PYRIDINES AS GPBAR1 AGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/117000    International Application No.:    PCT/EP2012/053386
Publication Date: 07.09.2012 International Filing Date: 29.02.2012
IPC:
C07D 213/75 (2006.01), C07D 213/81 (2006.01), C07D 213/82 (2006.01), C07D 401/04 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 405/04 (2006.01), C07D 405/12 (2006.01), C07D 413/04 (2006.01), C07D 413/12 (2006.01), C07D 417/04 (2006.01), C07D 417/12 (2006.01), C07D 491/107 (2006.01), A61K 31/4418 (2006.01), A61K 31/4433 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel (CH) (For All Designated States Except US).
BISSANTZ, Caterina [DE/FR]; (FR) (For US Only).
DEHMLOW, Henrietta [DE/DE]; (DE) (For US Only).
ERICKSON, Shawn David [US/US]; (US) (For US Only).
KARNACHI, Prabha Saba [US/US]; (US) (For US Only).
KIM, Kyungjin [US/US]; (US) (For US Only).
MARTIN, Rainer, E. [AT/CH]; (CH) (For US Only).
MATTEI, Patrizio [CH/CH]; (CH) (For US Only).
OBST SANDER, Ulrike [DE/CH]; (CH) (For US Only).
PIETRANICO-COLE, Sherrie Lynn [US/US]; (US) (For US Only).
RICHTER, Hans [DE/DE]; (DE) (For US Only).
ULLMER, Christoph [DE/DE]; (DE) (For US Only)
Inventors: BISSANTZ, Caterina; (FR).
DEHMLOW, Henrietta; (DE).
ERICKSON, Shawn David; (US).
KARNACHI, Prabha Saba; (US).
KIM, Kyungjin; (US).
MARTIN, Rainer, E.; (CH).
MATTEI, Patrizio; (CH).
OBST SANDER, Ulrike; (CH).
PIETRANICO-COLE, Sherrie Lynn; (US).
RICHTER, Hans; (DE).
ULLMER, Christoph; (DE)
Agent: KLOSTERMEYER RAUBER, Doerte; Grenzacherstrasse 124 CH-4070 Basel (CH)
Priority Data:
11156711.1 03.03.2011 EP
Title (EN) 3-AMINO-PYRIDINES AS GPBAR1 AGONISTS
(FR) 3-AMINOPYRIDINES EN TANT QU'AGONISTES DE GPBAR1
Abstract: front page image
(EN)This invention relates to novel 3-aminopyridines of the formula (I) wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
(FR)Cette invention concerne des nouvelles 3-aminopyridines de formule (I) où B1, B2 et R1 à R6 sont tels que définis dans la description et dans les revendications, ainsi que des sels pharmaceutiquement acceptables de celles-ci. Ces composés sont des agonistes de GPBAR1 et peuvent être utilisés en tant que médicaments pour le traitement de maladies telles que le diabète de type II.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)