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1. (WO2012115286) ALPHA HELIX MIMETICS AND METHODS RELATING THERETO
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/115286    International Application No.:    PCT/JP2012/055489
Publication Date: 30.08.2012 International Filing Date: 27.02.2012
IPC:
C07D 487/04 (2006.01), A61K 31/519 (2006.01), A61K 31/53 (2006.01), A61P 35/00 (2006.01)
Applicants: PRISM Pharma Co., Ltd. [JP/JP]; 4259-3, Nagatsuta-cho, Midori-ku, Yokohama-shi, Kanagawa 2268510 (JP) (For All Designated States Except US).
KOUJI, Hiroyuki [JP/JP]; (JP) (For US Only).
ODAGAMI, Takenao [JP/JP]; (JP) (For US Only)
Inventors: KOUJI, Hiroyuki; (JP).
ODAGAMI, Takenao; (JP)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
61/446,801 25.02.2011 US
Title (EN) ALPHA HELIX MIMETICS AND METHODS RELATING THERETO
(FR) MIMÉTIQUES D'HÉLICE ALPHA ET PROCÉDÉS S'Y RAPPORTANT
Abstract: front page image
(EN)Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating thereto, and methods relating thereto, are disclosed. Applications of these compounds in the treatment of medical conditions, e.g., cancer diseases, fibrotic diseases, and pharmaceutical compositions comprising the mimetics are further disclosed.
(FR)L'invention porte sur des structures et des composés mimétiques d'hélice alpha représentés par la formule (I), la formule générale et les définitions de chaque symbole étant telles que définies dans la description, sur un composé s'y rapportant et sur des procédés s'y rapportant. L'invention porte en outre sur des applications de ces composés dans le traitement d'affections médicales, par exemple de maladies cancéreuses ou de maladies fibreuses, et sur des compositions pharmaceutiques comprenant les mimétiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)