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1. (WO2012115222) ADJUVANT FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION AND PHARMACEUTICAL PREPARATION CONTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/115222    International Application No.:    PCT/JP2012/054544
Publication Date: 30.08.2012 International Filing Date: 24.02.2012
IPC:
A61K 39/39 (2006.01), A61K 9/02 (2006.01), A61K 9/06 (2006.01), A61K 9/14 (2006.01), A61K 9/70 (2006.01), A61K 39/00 (2006.01)
Applicants: HISAMITSU PHARMACEUTICAL CO., INC. [JP/JP]; 408, Tashirodaikanmachi, Tosu-shi, Saga 8410017 (JP) (For All Designated States Except US).
MORIMOTO, Kumi [JP/JP]; (JP) (For US Only).
TOKUMOTO, Seiji [JP/JP]; (JP) (For US Only)
Inventors: MORIMOTO, Kumi; (JP).
TOKUMOTO, Seiji; (JP)
Agent: KUZUWA, Kiyoshi; Patent Attorneys, KUZUWA & PARTNERS, Nishi-Shinjuku Mitsui Bldg. 17F, 6-24-1, Nishi-Shinjuku, Shinjuku-ku, Tokyo 1600023 (JP)
Priority Data:
2011-040283 25.02.2011 JP
Title (EN) ADJUVANT FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION AND PHARMACEUTICAL PREPARATION CONTAINING SAME
(FR) ADJUVANT POUR L'ADMINISTRATION TRANSDERMIQUE OU TRANSMUQUEUSE ET PRÉPARATION PHARMACEUTIQUE LE CONTENANT
(JA) 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤
Abstract: front page image
(EN)The present invention addresses the problem of providing a low-molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for efficiently enhancing the immunogenicity of an antigen. The present invention relates to an adjuvant for transdermal or transmucosal administration, containing at least one member selected from polyhydric alcohols and derivatives thereof including glycerol, glycerol derivatives and the like.
(FR)La présente invention concerne l'apport d'un adjuvant à faible poids moléculaire qui peut être administré de manière sûre sans induire une irritation cutanée ou similaire, par l'administration transdermique ou transmuqueuse et permet l'augmentation efficace de l'immunogénicité d'un antigène. La présente invention concerne un adjuvant pour l'administration transdermique ou transmuqueuse, contenant au moins un élément choisi parmi les alcools polyhydriques et des dérivés de ceux-ci, comprenant le glycérol, des dérivés du glycérol et similaires.
(JA) 本発明の課題は、経皮または経粘膜投与により皮膚刺激などを誘発することなく安全に投与可能であり、抗原の免疫原性を効率よく増強するための低分子アジュバントを提供することである。本発明は、グリセリンおよびグリセリン誘導体などを含む、多価アルコールおよびそれら誘導体から選択される少なくとも1種を含む、経皮または経粘膜投与のためのアジュバントに関する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)