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Pub. No.:    WO/2012/114312    International Application No.:    PCT/IB2012/050859
Publication Date: 30.08.2012 International Filing Date: 24.02.2012
C12Q 1/70 (2006.01), C07K 14/005 (2006.01), G01N 33/50 (2006.01), A61K 39/12 (2006.01), G01N 33/569 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH) (For All Designated States Except US).
ROTH, Bernhard [DE/DE]; (DE) (For US Only)
Inventors: ROTH, Bernhard; (DE)
Agent: MARSHALL, Cameron John; Carpmaels & Ransford One Southampton Row London WC1B 5HA (GB)
Priority Data:
61/463,980 25.02.2011 US
Abstract: front page image
(EN)The present invention provides an internal positive control for contaminating viruses. The invention provides the use of a second virus as an exogenous internal positive control in methods for verifying the reliability of an assay to detect a first virus, in methods of ensuring the absence of the first virus in a biological sample or pharmaceutical sample and in methods of manufacturing a vaccine free from a first virus.
(FR)La présente invention concerne un témoin positif interne pour des virus contaminants. L'invention concerne l'utilisation d'un second virus en tant que témoin positif interne exogène dans des procédés pour la vérification de la fiabilité d'un dosage pour détecter un premier virus, dans des procédés pour s'assurer de l'absence du premier virus dans un échantillon biologique ou dans un échantillon pharmaceutique et dans des procédés de fabrication d'un vaccin exempt d'un premier virus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)