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1. (WO2012114256) PROCESSES AND RECOMBINANT MICROORGANISMS FOR THE PRODUCTION OF CADAVERINE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/114256    International Application No.:    PCT/IB2012/050763
Publication Date: 30.08.2012 International Filing Date: 20.02.2012
IPC:
C12N 1/21 (2006.01), C12P 13/00 (2006.01), C12N 15/31 (2006.01), C12R 1/15 (2006.01)
Applicants: BASF SE [DE/DE]; 67056 Ludwigshafen (DE) (For All Designated States Except US).
WITTMANN, Christoph [DE/DE]; (DE) (For US Only).
KIND, Stefanie [DE/DE]; (DE) (For US Only).
BASF (CHINA) COMPANY LIMITED [CN/CN]; 300 Jiangxinsha Road Shanghai, 200137 (CN) (MN only)
Inventors: WITTMANN, Christoph; (DE).
KIND, Stefanie; (DE)
Common
Representative:
BASF SE; 67056 Ludwigshafen (DE)
Priority Data:
61/445098 22.02.2011 US
11155432.5 22.02.2011 EP
Title (EN) PROCESSES AND RECOMBINANT MICROORGANISMS FOR THE PRODUCTION OF CADAVERINE
(FR) PROCÉDÉS ET MICROORGANISMES RECOMBINANTS POUR LA PRODUCTION DE CADAVÉRINE
Abstract: front page image
(EN)Recombinant microorganisms comprising DNA molecules in a deregulated form which improve the production of cadaverine or N-acetylcadaverine, as well as recombinant DNA molecules and polypeptides used to produce the microorganisms are provided. Said microorganisms comprise an intracellular lysine decarboxylase activity and a deregulated cadaverine export activity, or comprise a decreased cadaverine export activity and an enhanced N-acetylcadaverine forming activity. Processes for the production of cadaverine N-acetylcadaverine using the recombinant microorganisms are also provided.
(FR)La présente invention concerne l'utilisation de microorganismes recombinants, comprenant des molécules d'ADN sous forme dérégulée, qui améliorent la production de cadavérine ou de N-acétylcadavérine, ainsi que des molécules d'ADN et des polypeptides recombinants utilisés pour produire les microorganismes, lesdits microorganismes ayant une activité de lysine décarboxylase intracellulaire et une activité d'exportation de cadavérine dérégulée ou ayant une activité d'exportation de cadavérine diminuée et une activité de formation de N-acétylcadavérine augmentée. La présente invention concerne également des procédés pour la production de cadavérine ou de N-acétylcadavérine faisant intervenir lesdits microorganismes recombinants.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)