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1. (WO2012113927) NOVEL SUPERACTIVE IL-33 FRAGMENTS, AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113927    International Application No.:    PCT/EP2012/053199
Publication Date: 30.08.2012 International Filing Date: 24.02.2012
IPC:
C07K 14/54 (2006.01), C07K 16/24 (2006.01)
Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR/FR]; 3, rue Michel Ange F-75016 Paris (FR) (For All Designated States Except US).
GIRARD, Jean-Philippe [FR/FR]; (FR) (For US Only).
CAYROL-GIRARD, Corinne [FR/FR]; (FR) (For US Only).
LEFRANCAIS, Emma [FR/FR]; (FR) (For US Only)
Inventors: GIRARD, Jean-Philippe; (FR).
CAYROL-GIRARD, Corinne; (FR).
LEFRANCAIS, Emma; (FR)
Agent: AHNER, Francis; Cabinet Regimbeau 20, rue de Chazelles F-75847 Paris Cedex 17 (FR)
Priority Data:
1151498 24.02.2011 FR
Title (EN) NOVEL SUPERACTIVE IL-33 FRAGMENTS, AND USES THEREOF
(FR) NOUVEAUX FRAGMENTS D'IL-33 SUPERACTIFS ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention discloses novel active polypeptide fragments of human IL-33 corresponding to natural forms generated by the proteases of human neutrophils (cathepsin G, elastase 2, proteinase 3), as well as the use thereof as a drug, in particular for the treatment of infectious diseases, inflammatory diseases, atherosclerosis, cardiovascular diseases, obesity, or cancer.
(FR)La présente invention divulgue de nouveaux fragments polypeptidiques actifs de l'IL-33 humaine correspondant à des formes naturelles générées par les protéases des neutrophiles humains (cathepsine G, elastase 2, protéinase 3), ainsi que leur utilisation en tant que médicament, notamment pour traiter les maladies infectieuses, les maladies inflammatoires, l'athérosclérose, les maladies cardio-vasculaires, l'obésité ou le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)