WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012113850) (PYRIDIN-4-YL)BENZYLAMIDES AS ALLOSTERIC MODULATORS OF ALPHA 7 nAChR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113850    International Application No.:    PCT/EP2012/053047
Publication Date: 30.08.2012 International Filing Date: 23.02.2012
IPC:
C07D 213/40 (2006.01), C07D 213/82 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 413/10 (2006.01), C07D 413/14 (2006.01), C07D 413/12 (2006.01), A61K 31/44 (2006.01), A61P 1/00 (2006.01), A61P 17/06 (2006.01), A61P 25/14 (2006.01), A61P 25/16 (2006.01), A61P 25/18 (2006.01), A61P 25/28 (2006.01), A61P 25/34 (2006.01)
Applicants: JANSSEN PHARMACEUTICA NV [BE/BE]; Turnhoutseweg 30 B-2340 Beerse (BE) (For All Designated States Except US).
DE BOECK, Benoît, Christian, Albert, Ghislain [BE/BE]; (BE) (For US Only).
ROMBOUTS, Geert [BE/BE]; (BE) (For US Only).
LEENAERTS, Joseph, Elisabeth [BE/BE]; (BE) (For US Only).
MACDONALD, Gregor, James [GB/BE]; (BE) (For US Only)
Inventors: DE BOECK, Benoît, Christian, Albert, Ghislain; (BE).
ROMBOUTS, Geert; (BE).
LEENAERTS, Joseph, Elisabeth; (BE).
MACDONALD, Gregor, James; (BE)
Common
Representative:
JANSSEN PHARMACEUTICA NV; Turnhoutseweg 30 B-2340 Beerse (BE)
Priority Data:
11155937.3 25.02.2011 EP
Title (EN) (PYRIDIN-4-YL)BENZYLAMIDES AS ALLOSTERIC MODULATORS OF ALPHA 7 nAChR
(FR) (PYRIDIN-4-YL)BENZYLAMIDES EN TANT QUE MODULATEURS ALLOSTÉRIQUES D'ALPHA-7-NACHR
Abstract: front page image
(EN)The present invention relates to (pyridin-4-yl)benzylamides derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulators having the capability to increase the efficacy of nicotinic receptor agonists.
(FR)La présente invention concerne des dérivés de (pyridin-4-yl)benzylamides et des sels pharmaceutiquement acceptables de ceux-ci, des procédés pour préparer ceux-ci, des compositions pharmaceutiques contenant ceux-ci et leur utilisation en thérapie. L'invention concerne en particulier des modulateurs allostériques positifs de récepteurs nicotiniques d'acétylcholine, de tels modulateurs allostériques positifs ayant la capacité d'augmenter l'efficacité d'agonistes de récepteur nicotinique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)