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1. (WO2012113834) METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS OF INFLAMMATORY BRAIN INJURY IN PRETERM BORN INFANTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113834    International Application No.:    PCT/EP2012/053016
Publication Date: 30.08.2012 International Filing Date: 22.02.2012
IPC:
G01N 33/68 (2006.01)
Applicants: InfanDx AG [DE/DE]; Balthasarstr. 18 50670 Köln (DE) (For All Designated States Except US).
KELLER, Matthias [DE/DE]; (DE) (For US Only).
MALLARD, Carina [SE/SE]; (SE) (For US Only).
DEIGNER, Hans-Peter [DE/DE]; (DE) (For US Only).
ENOT, David [FR/FR]; (FR) (For US Only).
IGWE, Emeka I. [DE/DE]; (DE) (For US Only)
Inventors: KELLER, Matthias; (DE).
MALLARD, Carina; (SE).
DEIGNER, Hans-Peter; (DE).
ENOT, David; (FR).
IGWE, Emeka I.; (DE)
Agent: WINTER BRANDL FÜRNISS HÜBNER RÖSS KAISER POLTE - Partnerschaft; Alois-Steinecker-Str. 22 85354 Freising (DE)
Priority Data:
11155450.7 22.02.2011 EP
Title (EN) METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS OF INFLAMMATORY BRAIN INJURY IN PRETERM BORN INFANTS
(FR) UTILISATION DE MÉTABOLITES POUR LE DIAGNOSTIC DE LÉSIONS CÉRÉBRALES INFLAMMATOIRES CHEZ LES NOUVEAU-NÉS PRÉMATURÉS ET PROCÉDÉ ASSOCIÉ
Abstract: front page image
(EN)The present invention relates to novel biomarkers for predicting the likelihood of inflammation-related brain injury in preterm born infants, using a plurality of endogenous target metabolites selected from the group consisting of acyl carnitins, diacylphosphatidylcholines, acyl-alkylphosphatidylchoines, lysophosphatidylcholines and amino acids.
(FR)L'invention concerne de nouveaux biomarqueurs permettant de prédire le risque de lésion cérébrale inflammatoire chez les nouveau-nés prématurés, au moyen d'une pluralité de métabolites cibles endogènes choisis dans le groupe composé des acyle-carnitines, des diacylphosphatidylcholines, des acyl-alkylphosphatidylcholines, des lysophosphatidylcholines et des acides aminés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)