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1. (WO2012113773) DIAGNOSIS OF ISCHEMIA USING SFLT-1 AND HGF AFTER INTERVENTION AS AN EARLY INDICATOR OF COMPLICATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113773    International Application No.:    PCT/EP2012/052905
Publication Date: 30.08.2012 International Filing Date: 21.02.2012
Chapter 2 Demand Filed:    21.12.2012    
IPC:
C12Q 1/48 (2006.01), G01N 33/74 (2006.01)
Applicants: ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Strasse 116 68305 Mannheim (DE) (DE only).
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacher Strasse 124 CH-4070 Basel (CH) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
HESS, Georg [DE/DE]; (DE) (For US Only).
HORSCH, Andrea [DE/DE]; (DE) (For US Only).
ZDUNEK, Dietmar [DE/DE]; (DE) (For US Only)
Inventors: HESS, Georg; (DE).
HORSCH, Andrea; (DE).
ZDUNEK, Dietmar; (DE)
Agent: HUHN, Michael; N 4, 1 68161 Mannheim (DE)
Priority Data:
11155457.2 22.02.2011 EP
Title (EN) DIAGNOSIS OF ISCHEMIA USING SFLT-1 AND HGF AFTER INTERVENTION AS AN EARLY INDICATOR OF COMPLICATION
(FR) DIAGNOSTIC D'ISCHÉMIE AU MOYEN DE SFLT-1 ET DE HGF APRÈS UNE INTERVENTION COMME INDICATEUR PRÉCOCE DE COMPLICATION
Abstract: front page image
(EN)The present invention relates to the field of laboratory diagnostics. Specifically means and methods for diagnosing complications of procedures such as angiography or angioplasty in a subject are described. Moreover, the subclassification of the type of complication is disclosed. The invention describes the use of hepatocyte growth factor, soluble fms-like tyrosine kinase 1, cardiac troponins, urinary liver type fatty acid binding protein, adiponectin, neutrophil gelatinase associated lipocalin (NGAL), albumin and kidney injury molecule 1 for the aforementioned purposes.
(FR)La présente invention concerne le domaine des diagnostics de laboratoire. Spécifiquement, elle concerne des moyens et des procédés pour le diagnostic de complications de protocoles comme l'angiographie ou l'angioplastie chez un sujet. En outre, elle concerne la sous-classification du type de complication. L'invention concerne l'utilisation du facteur de croissance des hépatocytes, de la tyrosine kinase de type fms 1 soluble, des troponines cardiaques, de la protéine liant les acides gras urinaires de type hépatique, de l'adiponectine, de la lipocaline associée à la gélatinase des polynucléaires neutrophiles (NGAL), de l'albumine et de la kidney injury molecule 1 dans les objectifs mentionnés ci-dessus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)