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1. (WO2012113718) A DIAGNOSTIC METHOD FOR TYPE II DIABETES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113718    International Application No.:    PCT/EP2012/052732
Publication Date: 30.08.2012 International Filing Date: 17.02.2012
Chapter 2 Demand Filed:    17.12.2012    
IPC:
C07K 16/28 (2006.01), G01N 33/53 (2006.01)
Applicants: ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Straße 116 68305 Mannheim (DE) (DE only).
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacher Strasse 124 CH-4070 Basel (CH) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ENGEL, Alfred [DE/DE]; (DE) (For US Only).
HAEFLIGER, Carolina [CH/CH]; (CH) (For US Only).
KUBALEC, Pavel [SK/DE]; (DE) (For US Only).
ROESSLER, Markus [DE/DE]; (DE) (For US Only).
SCHRAEML, Michael [DE/DE]; (DE) (For US Only).
SOUKUPOVA, Monika [CZ/DE]; (DE) (For US Only)
Inventors: ENGEL, Alfred; (DE).
HAEFLIGER, Carolina; (CH).
KUBALEC, Pavel; (DE).
ROESSLER, Markus; (DE).
SCHRAEML, Michael; (DE).
SOUKUPOVA, Monika; (DE)
Agent: NASER, Werner; Roche Diagnostics GmbH P.O. Box 11 52 Nonnenwald 2 82372 Penzberg (DE)
Priority Data:
11155259.2 21.02.2011 EP
Title (EN) A DIAGNOSTIC METHOD FOR TYPE II DIABETES
(FR) PROCÉDÉ DE DIAGNOSTIC DU DIABÈTE TYPE II
Abstract: front page image
(EN)The present invention relates to an in vitro method aiding in the assessment of type II diabetes (T2D). It discloses the use of the protein TMEM 27 as a marker of T2D. Furthermore, it especially relates to a method for assessing T2D from a sample, derived from an individual by measuring the protein TMEM27 in said sample in vitro. The invention further relates to antibodies against human TMEM27 protein, methods for their production, and uses thereof.
(FR)La présente invention concerne un procédé in vitro contribuant à l'évaluation du diabète type II (DT2). Elle concerne l'utilisation de la protéine TMEM 27 comme marqueur du DT2. En outre, elle concerne particulièrement un procédé d'évaluation du DT2 à partir d'un échantillon, obtenu sur un individu, en mesurant la protéine TMEM27 dans ledit échantillon in vitro. L'invention concerne en outre des anticorps contre la protéine TMEM27 humaine, des procédés pour les produire, et leurs utilisations.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)