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1. (WO2012113564) STABILIZED GRANULES CONTAINING GLYCERYL TRINITRATE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113564    International Application No.:    PCT/EP2012/000803
Publication Date: 30.08.2012 International Filing Date: 24.02.2012
IPC:
A61K 9/00 (2006.01), A61K 9/14 (2006.01), A61K 31/21 (2006.01), A61K 47/02 (2006.01), A61K 47/14 (2006.01), A61K 47/26 (2006.01), A61P 9/10 (2006.01)
Applicants: G. POHL-BOSKAMP GMBH & CO. KG [DE/DE]; Kieler Straße 11 25551 Hohenlockstedt (DE) (For All Designated States Except US).
ZIMMECK, Thomas [DE/DE]; (DE) (For US Only).
UECK, Henning [DE/DE]; (DE) (For US Only).
ZSCHERPE, Julia [DE/DE]; (DE) (For US Only)
Inventors: ZIMMECK, Thomas; (DE).
UECK, Henning; (DE).
ZSCHERPE, Julia; (DE)
Agent: MAIWALD PATENTANWALTS GMBH; Volker Hamm Jungfernstieg 38 20354 Hamburg (DE)
Priority Data:
10 2011 012 491.8 25.02.2011 DE
Title (EN) STABILIZED GRANULES CONTAINING GLYCERYL TRINITRATE
(FR) GRANULES STABILISÉS CONTENANT DU TRINITRATE DE GLYCÉRYLE
Abstract: front page image
(EN)Solid pharmaceutical preparation with the active substance glyceryl trinitrate for oromucosal or oral administration characterized in that it contains between 0.05 and 2 weight% glyceryl trinitrate, at least one carrier material, and at least one substance that reduces the volatility of the GTN, whereby this substance is a non-volatile ester stabilizer.
(FR)La présente invention concerne une préparation pharmaceutique solide contenant, en tant que substance active, du trinitrate de glycéryle et destinée à une administration oromuqueuse ou orale. Ladite préparation pharmaceutique est caractérisée en ce qu'elle contient de 0,05 à 2 % en poids de trinitrate de glycéryle, au moins un matériau vecteur, et au moins une substance qui réduit la volatilité du GTN, cette substance étant ainsi un stabilisateur d'ester non volatil.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)