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1. (WO2012113371) DETECTION OF DIMERIC CATECHOLAMINE METABOLITES AS INDICATORS OF NEURODEGENERATIVE DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113371    International Application No.:    PCT/DE2012/000147
Publication Date: 30.08.2012 International Filing Date: 17.02.2012
IPC:
G01N 33/94 (2006.01)
Applicants: THANARES GMBH [DE/EC]; Hermannswerder 14 14473 Potsdam (DE) (For All Designated States Except US).
THIEDE, Hans-Michael [DE/DE]; (DE) (For US Only).
KEHR, Wolfgang [DE/DE]; (DE) (For US Only)
Inventors: THIEDE, Hans-Michael; (DE).
KEHR, Wolfgang; (DE)
Agent: JUNGBLUT, Bernhard; Jungblut & Seuss Max-Dohrn-Strasse 10 10589 Berlin (DE)
Priority Data:
10 2011 011 813.6 21.02.2011 DE
10 2011 121 884.3 21.06.2011 DE
Title (DE) NACHWEIS VON DIMEREN CATECHOLAMINMETABOLITEN ALS INDIKATOREN FÜR NEURODEGENERATIVE ERKRANKUNGEN
(EN) DETECTION OF DIMERIC CATECHOLAMINE METABOLITES AS INDICATORS OF NEURODEGENERATIVE DISEASES
(FR) DÉTECTION DE CATECHOLAMINE-MÉTABOLITES DIMÈRES COMME INDICATEURS DE MALADIES NEURO-DÉGÉNÉRATIVES
Abstract: front page image
(DE)Die Erfindung betrifft Verfahren zur Bestimmung mindestens eines dimeren oder trimeren Catecholaminmetaboliten, insbesondere dimerer Homovanillinsäure, in einer Körperflüssigkeit, wie Urin, wobei die Körperflüssigkeit einer Nachweismethode zur qualitativen oder quantitativen Bestimmung des dimeren oder trimeren Catecholaminmetaboliten unterworfen wird. Solche Verfahren sind geeignet zur Frühdiagnose neurodegenerativer Erkrankungen, wie der Parkinson'schen Krankheit oder der Alzheimer'schen Krankheit.
(EN)The invention relates to methods for detecting at least one dimeric or trimeric catecholamine metabolite, especially dimeric homovanillic acid, in a body fluid, such as urine, said body fluid being subjected to a detection method for the qualitative or quantitative detection of the dimeric or trimeric catecholamine metabolite. Said methods are suitable for the early diagnosis of neurodegenerative diseases, such as Parkinson's disease or Alzheimer's disease.
(FR)L'invention concerne un procédé de détermination d'au moins un catecholamine-métabolite dimère ou trimère, notamment de l'acide omovanillique dimère, dans un liquide organique, comme l'urine, le liquide organique étant soumis à une méthode de détection pour une détermination qualitative ou quantitative du catecholamine-métabolite dimère ou trimère. De tels procédés sont adaptés au diagnostic précoce de maladies neuro-dégénératives, comme la maladie de Parkinson ou la maladie d'Alzheimer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)