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1. (WO2012113236) USE AND METHOD OF HEPATOCYTE NUCLEAR FACTOR 1Α FOR TREATING CHRONIC LIVER DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/113236    International Application No.:    PCT/CN2011/081172
Publication Date: 30.08.2012 International Filing Date: 24.10.2011
IPC:
A61K 48/00 (2006.01), A61K 38/17 (2006.01), A61P 1/16 (2006.01)
Applicants: SECOND MILITARY MEDICAL UNIVERSITY OF THE PEOPLE'S LIBERATION ARMY [CN/CN]; No.800, Xiangyin Road Yangpu District, Shanghai 200433 (CN) (For All Designated States Except US).
XIE, Weifen [CN/CN]; (CN) (For US Only).
LIN, Yong [CN/CN]; (CN) (For US Only).
ZENG, Xin [CN/CN]; (CN) (For US Only)
Inventors: XIE, Weifen; (CN).
LIN, Yong; (CN).
ZENG, Xin; (CN)
Agent: SHANGHAI ZHUOYANG INTELLECTUAL PROPERTY AGENT FIRM; Room 605, Yucheng Building No.9, Lane 1283 North Shanxi Road Putuo District, Shanghai 200060 (CN)
Priority Data:
201110043321.6 23.02.2011 CN
Title (EN) USE AND METHOD OF HEPATOCYTE NUCLEAR FACTOR 1Α FOR TREATING CHRONIC LIVER DISEASES
(FR) UTILISATION DU FACTEUR NUCLÉAIRE HÉPATOCYTAIRE 1A POUR LE TRAITEMENT DE MALADIES HÉPATIQUES CHRONIQUES ET PROCÉDÉ ASSOCIÉ
(ZH) 肝细胞核因子1α治疗慢性肝病的用途及方法
Abstract: front page image
(EN)Provided are a use and a method for treating chronic liver diseases such as liver fibrosis and liver cirrhosis by using hepatocyte nuclear factor 1α (HNF1α). Regulation of the expression of HNF1α gene can effectively induce the hepatocyte nuclear factor, thus providing a new means for treating chronic liver diseases.
(FR)La présente invention concerne une utilisation et un procédé de traitement de maladies hépatiques chroniques telles qu'une fibrose hépatique et une cirrhose hépatique à l'aide du facteur nucléaire hépatocytaire 1α (HNF1α). La régulation de l'expression du gène HNF1α peut efficacement induire le facteur nucléaire hépatocytaire, fournissant ainsi un nouveau moyen de traitement de maladies hépatiques chroniques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)