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1. (WO2012112969) AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/112969    International Application No.:    PCT/US2012/025759
Publication Date: 23.08.2012 International Filing Date: 18.02.2012
IPC:
C07D 207/09 (2006.01), C07D 211/26 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 417/12 (2006.01), C07D 471/10 (2006.01), C07D 498/10 (2006.01), A61K 31/452 (2006.01), A61P 23/02 (2006.01), A61P 29/02 (2006.01)
Applicants: ENDO PHARMACEUTICALS INC. [US/US]; 1400 Atwater Drive Malvern, PA 19355 (US) (For All Designated States Except US).
THOMPSON, Scott, Kevin [US/US]; (US) (For US Only).
PRIESTLEY, Tony [GB/US]; (US) (For US Only).
SMITH, Roger, Astbury [US/US]; (US) (For US Only).
SAHA, Ashis, K. [US/US]; (US) (For US Only).
RUDRA, Sonali [IN/IN]; (IN) (For US Only).
HAJRA, Arun, Kuma [IN/IN]; (IN) (For US Only).
CHATTERJEE, Dipanwita [IN/IN]; (IN) (For US Only).
BEHRENS, Carl, Henry [US/US]; (US) (For US Only).
HE, Yigang [CN/US]; (US) (For US Only).
LI, Hui-Yin [US/US]; (US) (For US Only)
Inventors: THOMPSON, Scott, Kevin; (US).
PRIESTLEY, Tony; (US).
SMITH, Roger, Astbury; (US).
SAHA, Ashis, K.; (US).
RUDRA, Sonali; (IN).
HAJRA, Arun, Kuma; (IN).
CHATTERJEE, Dipanwita; (IN).
BEHRENS, Carl, Henry; (US).
HE, Yigang; (US).
LI, Hui-Yin; (US)
Agent: PALOVICH, Tracy, U.; Howson & Howson LLP 501 Office Center Drive Suite 210 Fort Washington, PA 19034 (US)
Priority Data:
61/444,379 18.02.2011 US
Title (EN) AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN
(FR) COMPOSÉS D'AMINO-INDANE ET LEUR UTILISATION DANS LE TRAITEMENT DE LA DOULEUR
Abstract: front page image
(EN)The present application provides novel aminoindane compounds and methods for preparing and using these compounds. These compounds are useful in treating pain and/or itch in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) or (II) and a TRPVl receptor activator. In one embodiment, the TRPVl receptor activator is lidocaine.
(FR)La présente invention concerne de nouveaux composés d'amino-indane et des procédés pour préparer et utiliser ces composés. Ces composés sont utiles pour traiter chez des patients la douleur et/ou des démangeaisons par administration d'un ou de plusieurs des composés à un patient. Le procédé comprend l'administration d'un composé de formule (I) ou (II) et d'un activateur du récepteur TRPVl. Dans un mode de réalisation, l'activateur du récepteur TRPVl est la lidocaïne.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)