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Machine translation
1. (WO2012112958) HIGH-THROUGHPUT ASSAYS TO PROBE LEUKEMIA WITHIN THE STROMAL NICHE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/112958    International Application No.:    PCT/US2012/025745
Publication Date: 23.08.2012 International Filing Date: 17.02.2012
IPC:
G01N 33/15 (2006.01), C12N 5/071 (2010.01), G06T 7/00 (2006.01)
Applicants: THE BROAD INSTITUTE, INC [US/US]; 7 Cambridge Center, 7034 Cambridge, Massachusetts 02142 (US) (For All Designated States Except US).
THE GENERAL HOSPITAL CORPORATION [US/US]; 55 Fruit Street Boston, Massachusetts 02114 (US) (For All Designated States Except US).
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US/US]; 75 Francis Street Boston, Massachusetts 02115 (US) (For All Designated States Except US).
PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 1350 Massachusetts Ave. Cambridge, Massachusetts 02138 (US) (For All Designated States Except US).
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH [US/US]; 1275 York Avenue New York, New York 10021 (US) (For All Designated States Except US).
DANA FARBER CANCER INSTITUTE, INC. [US/US]; 44 Binney Street Boston, Massachusetts 02115 (US) (For All Designated States Except US).
HARTWELL, Kimberly [US/US]; (US) (For US Only).
GILLILAND, D. Gary [US/US]; (US) (For US Only).
MOORE, Malcolm A.S. [US/US]; (US) (For US Only).
SCADDEN, David [US/US]; (US) (For US Only).
SCHREIBER, Stuart [US/US]; (US) (For US Only).
GOLUB, Todd [US/US]; (US) (For US Only).
EBERT, Benjamin [US/US]; (US) (For US Only).
CARPENTER VAN DYK, Anne [US/US]; (US) (For US Only).
LOGAN, David [US/US]; (US) (For US Only).
STERN, Andrew [US/US]; (US) (For US Only).
MILLER, Peter [US/US]; (US) (For US Only).
NEGRI, Joseph [US/US]; (US) (For US Only).
TOLLIDAY, Nicola [GB/US]; (US) (For US Only).
STEWART, Alison [US/US]; (US) (For US Only).
SHAMJI, Alykhan [CA/US]; (US) (For US Only).
MUKHERJEE, Siddhartha [US/US]; (US) (For US Only)
Inventors: HARTWELL, Kimberly; (US).
GILLILAND, D. Gary; (US).
MOORE, Malcolm A.S.; (US).
SCADDEN, David; (US).
SCHREIBER, Stuart; (US).
GOLUB, Todd; (US).
EBERT, Benjamin; (US).
CARPENTER VAN DYK, Anne; (US).
LOGAN, David; (US).
STERN, Andrew; (US).
MILLER, Peter; (US).
NEGRI, Joseph; (US).
TOLLIDAY, Nicola; (US).
STEWART, Alison; (US).
SHAMJI, Alykhan; (US).
MUKHERJEE, Siddhartha; (US)
Agent: KUGLER DEYOUNG, Janice; Fish & Richardson, P.C. P.O. Box 1022 Minneapolis, Minnesota 55440-1022 (US)
Priority Data:
61/444,701 19.02.2011 US
Title (EN) HIGH-THROUGHPUT ASSAYS TO PROBE LEUKEMIA WITHIN THE STROMAL NICHE
(FR) DOSAGES À GRAND RENDEMENT DESTINÉS À DÉTECTER LA LEUCÉMIE DANS LA NICHE STROMALE
Abstract: front page image
(EN)This invention relates to high-throughput, semi-automated methods for identifying compounds that are effective in targeting leukemia stem cells, as well as compounds identified by those methods and uses thereof for treating leukemia.
(FR)La présente invention concerne des procédés semi-automatiques à grand rendement destinés à identifier des composés qui sont efficaces pour cibler les cellules souches leucémiques, ainsi que les composés identifiés par ces procédés et les utilisations associées pour le traitement de la leucémie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)