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Machine translation
1. (WO2012112869) TARGETED CANCER THERAPY USING ETS TRANSCRIPTIONAL INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/112869    International Application No.:    PCT/US2012/025608
Publication Date: 23.08.2012 International Filing Date: 17.02.2012
IPC:
C07K 14/435 (2006.01), A61K 38/17 (2006.01), A61P 35/00 (2006.01)
Applicants: SCOTT & WHITE HEALTHCARE [US/US]; 4326 Lowes Drive Temple, TX 76502 (US) (For All Designated States Except US).
CAO, Xiaobo [US/US]; (US) (For US Only).
SMYTHE, William, Roy [US/US]; (US) (For US Only).
GIZACHEW, Dawit [US/US]; (US) (For US Only)
Inventors: CAO, Xiaobo; (US).
SMYTHE, William, Roy; (US).
GIZACHEW, Dawit; (US)
Agent: SISTRUNK, Melissa, L.; Fulbright & Jaworski L.L.P. Fulbright Tower 1301 Mckinney, Suite 5100 Houston, TX 77010-3095 (US)
Priority Data:
61/443,918 17.02.2011 US
Title (EN) TARGETED CANCER THERAPY USING ETS TRANSCRIPTIONAL INHIBITORS
(FR) THÉRAPIE ANTICANCÉREUSE CIBLÉE UTILISANT DES INHIBITEURS DE LA TRANSCRIPTION D'ETS
Abstract: front page image
(EN)The present invention generally concerns methods and compositions for treating an individual with cancer utilizing polypeptide mutants of TEL. In particular embodiments, TEL polypeptides or peptides are employed having mutations at one or more of phosphorylation, acetylation, glycosylation, ubiquitination, or sumoylation sites, for example.
(FR)La présente invention concerne généralement des procédés et des compositions de traitement d'un individu atteint du cancer en utilisant des polypeptides mutants de TEL. Dans des modes de réalisation particuliers, les peptides ou polypeptides TEL qui sont utilisés présentent des mutations au niveau d'un ou plusieurs sites de phosphorylation, d'acétylation, de glycosylation, d'ubiquitination, ou de sumoylation, par exemple.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)