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1. (WO2012112804) COMPOSITIONS AND METHODS FOR MOLECULAR LABELING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/112804    International Application No.:    PCT/US2012/025499
Publication Date: 23.08.2012 International Filing Date: 16.02.2012
IPC:
C07H 21/00 (2006.01), C40B 40/06 (2006.01)
Applicants: RAINDANCE TECHNOLIGIES, INC. [US/US]; 44 Hartwell Avenue Lexington, MA 02421 (US) (For All Designated States Except US).
SAMUELS, Michael [US/US]; (US) (For US Only).
OLSON, Jeffrey, Charles [US/US]; (US) (For US Only).
WATSON, Andrew [US/US]; (US) (For US Only).
BROWN, Keith [US/US]; (US) (For US Only).
LINK, Darren [US/US]; (US) (For US Only)
Inventors: SAMUELS, Michael; (US).
OLSON, Jeffrey, Charles; (US).
WATSON, Andrew; (US).
BROWN, Keith; (US).
LINK, Darren; (US)
Agent: MEYERS, Thomas, C.; Brown Rudnick LLP One Financial Center Boston, MA 02111 (US)
Priority Data:
61/476,714 18.04.2011 US
61/444,612 18.02.2011 US
Title (EN) COMPOSITIONS AND METHODS FOR MOLECULAR LABELING
(FR) COMPOSITIONS ET MÉTHODES DE MARQUAGE MOLÉCULAIRE
Abstract: front page image
(EN)The invention provides barcode libraries and methods of making and using them including obtaining a plurality of nucleic acid constructs in which each construct comprises a unique N-mer and a functional N-mer and segregating the constructs into a fluid compartments such that each compartment contains one or more copies of a unique construct. The invention further provides methods for digital PCR and for use of barcode libraries in digital PCR.
(FR)La présente invention concerne des bibliothèques de codes-barres et leurs procédés de fabrication et d'utilisation, y compris l'obtention d'une multitude de constructions d'acides nucléiques, chaque construction comprenant un N-mère unique et un N-mère fonctionnel, et le classement des constructions dans des compartiments fluidiques de façon à ce que chaque compartiment contienne une ou plusieurs copies d'une construction unique. La présente invention concerne en outre des procédés de PCR numérique et l'utilisation des bibliothèques de codes-barres en PCR numérique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)