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Pub. No.:    WO/2012/112792    International Application No.:    PCT/US2012/025479
Publication Date: 23.08.2012 International Filing Date: 16.02.2012
A61K 48/00 (2006.01), A61K 38/17 (2006.01), A61K 38/16 (2006.01), A61P 35/00 (2006.01)
Applicants: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND [US/US]; 1430 Tulane Avenue, Tb-32 New Orleans, LA 70112-2632 (US) (For All Designated States Except US).
COY, David, H. [US/US]; (US) (For US Only).
SUN, Lichun [CN/US]; (US) (For US Only)
Inventors: COY, David, H.; (US).
SUN, Lichun; (US)
Agent: GUTTMAN, Harry, J.; Stipkala LLC 5401 Netherby Lane Suite 102A North Charleston, SC 29420 (US)
Priority Data:
61/558,227 10.11.2011 US
61/463,482 17.02.2011 US
Abstract: front page image
(EN)Multicomponent compositions and methods of use thereof are disclosed herein. Some embodiments of the present invention include multicomponent compositions comprising a first component and a second component, where the first component comprises a notch influencing molecule and the second component comprises a GPCR targeted molecule. Kits comprising the multicomponent composition are also disclosed. Methods for providing the multicomponent composition to one or more cells are additionally provided. Further embodiments include methods of using the multicomponent composition such as, for example, methods of administering the multicomponent composition and method of treating organisms (such as mammals) using the multicomponent composition.
(FR)L'invention concerne des compositions multicomposants et des procédés pour les utiliser. Certains modes de réalisation de la présente invention concernent des compositions multicomposants comprenant un premier composant et un deuxième composant, le premier composant comprenant une molécule influençant Notch et le deuxième composant comprenant une molécule ciblée sur les GPCR. L'invention concerne également des kits comprenant la composition multicomposant. Elle concerne en outre des procédés d'administration de la composition multicomposant à une ou plusieurs cellules. D'autres modes de réalisation concernent des procédés d'utilisation de la composition multicomposant comme, par exemple, des procédés d'administration de la composition multicomposant et un procédé de traitement d'organismes (comme des mammifères) au moyen de la composition multicomposant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)