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1. (WO2012110912) SUSTAINED RELEASE COMPOSITION OF MEMANTINE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/110912    International Application No.:    PCT/IB2012/050539
Publication Date: 23.08.2012 International Filing Date: 07.02.2012
IPC:
A61K 9/16 (2006.01), A61K 9/50 (2006.01), A61K 31/13 (2006.01)
Applicants: LUPIN LIMITED [IN/IN]; 159 CST Road, Kalina, Santacruz (East), State of Maharashtra, Mumbai 400 098 (IN) (For All Designated States Except US).
BHUTADA, Pravin, Meghrajji [IN/IN]; (IN) (For US Only).
DESHMUKH, Ashish, Ashokrao [IN/IN]; (IN) (For US Only).
CHANDRAN, Sajeev [IN/IN]; (IN) (For US Only).
RAGHAVAN, Vineeth [IN/IN]; (IN) (For US Only).
KULKARNI, Shirishkumar [IN/IN]; (IN) (For US Only)
Inventors: BHUTADA, Pravin, Meghrajji; (IN).
DESHMUKH, Ashish, Ashokrao; (IN).
CHANDRAN, Sajeev; (IN).
RAGHAVAN, Vineeth; (IN).
KULKARNI, Shirishkumar; (IN)
Agent: MAJUMDAR, Subhatosh; S. Majumdar & Co. 5, Harish Mukherjee Road Kolkata 700 025 (IN)
Priority Data:
201/KOL/2011 17.02.2011 IN
Title (EN) SUSTAINED RELEASE COMPOSITION OF MEMANTINE
(FR) COMPOSITION À LIBÉRATION PROLONGÉE DE MÉMANTINE
Abstract: front page image
(EN)The present invention is a sustained release pharmaceutical composition comprising; a core comprising memantine or its pharmaceutically acceptable salts and one or more pharmaceutical acceptable excipient(s), and a sustained release coating comprising the water insoluble substance and a water soluble substance wherein ratio of the water insoluble substance to the water soluble substance is from about 1:0 to about 3.5:1, optionally containing an immediate release coating comprising memantine over the sustained release coating.
(FR)La présente invention concerne une composition pharmaceutique à libération prolongée comprenant : un composant de noyau comprenant de la mémantine ou ses sels pharmaceutiquement acceptables et un ou plusieurs excipient(s) pharmaceutiquement acceptable(s), et un enrobage à libération prolongée comprenant une substance insoluble dans l'eau et une substance soluble dans l'eau, le rapport de la substance insoluble dans l'eau à la substance soluble dans l'eau étant d'environ 1:0 à environ 3,5:1, contenant facultativement un enrobage à libération immédiate comprenant de la mémantine sur l'enrobage à libération prolongée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)