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1. WO2012109600 - METHODS FOR FORMING MIXED DROPLETS

Publication Number WO/2012/109600
Publication Date 16.08.2012
International Application No. PCT/US2012/024741
International Filing Date 10.02.2012
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
B01F 13/0062
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
13Other mixers; Mixing plant, including combinations of ; mixers, e.g. of; dissimilar mixers
0059Micromixers
0061using specific means for arranging the streams to be mixed
0062Hydrodynamic focussing
B01F 13/0071
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
13Other mixers; Mixing plant, including combinations of ; mixers, e.g. of; dissimilar mixers
0059Micromixers
0069the components flowing in the form of droplets
0071the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
B01F 13/0076
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
13Other mixers; Mixing plant, including combinations of ; mixers, e.g. of; dissimilar mixers
0059Micromixers
0074using mixing means not otherwise provided for
0076using electrohydrodynamic [EHD] or electrokinetic [EKI] phenomena to mix or move the fluids
B01F 2215/0037
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
2215Auxiliary or complementary information in relation with mixing
0001Field of application of the mixing device
0037Mixers used as laboratory equipment, e.g. for analyzing, testing and investigating chemical, physical or biological properties of materials
B01F 3/0803
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
3Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed
08liquids with liquids; Emulsifying
0803Methods
B01F 3/0865
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
3Mixing, e.g. dispersing, emulsifying, according to the phases to be mixed
08liquids with liquids; Emulsifying
0861Mixing liquids using flow mixing
0865by injecting or introducing one liquid into another
Applicants
  • RAINDANCE TECHNOLOGIES, INC. [US]/[US] (AllExceptUS)
  • YURKOVETSKY, Yevgeny [US]/[US] (UsOnly)
  • LINK, Darren [US]/[US] (UsOnly)
  • LARSON, Jonathan, William [US]/[US] (UsOnly)
Inventors
  • YURKOVETSKY, Yevgeny
  • LINK, Darren
  • LARSON, Jonathan, William
Agents
  • MEYERS, Thomas C.
Priority Data
61/441,98511.02.2011US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR FORMING MIXED DROPLETS
(FR) PROCÉDÉS DE FORMATION DE GOUTTELETTES MÉLANGÉES
Abstract
(EN)
Methods involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet. Methods for merging two liquid phases in which only one phase is in the form of a droplet at least at the point of merging A second phase is injected into the drops directly from a continuous stream. Methods of the invention provide a simple and reliable approach to sample fluid mixing because only one of the two phases is dispersed as a droplet prior to its merge with the other phase.
(FR)
L'invention porte d'une manière générale sur des procédés de formation de gouttelettes mélangées. Dans certains modes de réalisation, des procédés de l'invention consistent à former une gouttelette et à mettre la gouttelette en contact avec un courant de fluide, une partie du courant de fluide étant intégrée avec la gouttelette pour former une gouttelette mélangée.
Also published as
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