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1. (WO2012109544) NOVEL 1-(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/109544    International Application No.:    PCT/US2012/024659
Publication Date: 16.08.2012 International Filing Date: 10.02.2012
IPC:
C07D 217/24 (2006.01), C07D 401/06 (2006.01), C07D 401/14 (2006.01), C07D 405/14 (2006.01), A61K 31/4725 (2006.01), A61P 27/02 (2006.01)
Applicants: ALLERGAN, INC. [US/US]; 2525 Dupont Drive Irvine, California 92886 (US) (For All Designated States Except US).
BEARD, Richard L. [US/US]; (US) (For US Only).
DONELLO, John E. [US/US]; (US) (For US Only).
GARST, Michael E. [US/US]; (US) (For US Only).
VISWANATH, Veena [US/US]; (US) (For US Only).
DUONG, Tien T. [US/US]; (US) (For US Only)
Inventors: BEARD, Richard L.; (US).
DONELLO, John E.; (US).
GARST, Michael E.; (US).
VISWANATH, Veena; (US).
DUONG, Tien T.; (US)
Agent: ENE, Doina; Allergan, Inc. 2525 Dupont Drive Irvine, California 92612 (US)
Priority Data:
61/441,824 11.02.2011 US
Title (EN) NOVEL 1-(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS
(FR) NOUVEAUX DÉRIVÉS DE 1-(1-OXO-1,2,3,4-TÉTRAHYDROISOQUINOLIN-7-YL)URÉE EN TANT QUE MODULATEURS DU RÉCEPTEUR DE TYPE 1 DE N-FORMYL PEPTIDE (FPRL-1)
Abstract: front page image
(EN)The present invention relates to novel 1-(1-Oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor.
(FR)La présente invention concerne de nouveaux dérivés de 1-(1-Oxo-1,2,3,4-tétrahydroisoquinolin-7-yl)urée, leurs procédés de préparation, des compositions pharmaceutiques les contenant et leur utilisation en tant que produits pharmaceutiques en tant que modulateurs du récepteur de type 1 de N-formyl peptide (FPRL-1).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)