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Pub. No.:    WO/2012/109199    International Application No.:    PCT/US2012/024085
Publication Date: 16.08.2012 International Filing Date: 07.02.2012
C12N 15/87 (2006.01), A61K 48/00 (2006.01)
Applicants: INNOVATIVE SURFACE TECHNOLOGIES, INC. [US/US]; 1000 Westgate Drive Suite 115 St. Paul, MN 55114 (US) (For All Designated States Except US).
GUIRE, Eric [US/US]; (US) (For US Only).
WEN, Jie [CN/US]; (US) (For US Only)
Inventors: GUIRE, Eric; (US).
WEN, Jie; (US)
Agent: WHIPPS, Brian, C.; Mueting, Raasch & Gebhardt, P.A. P.O. Box 581336 Minneapolis, MN 55458-1336 (US)
Priority Data:
61/440,387 07.02.2011 US
Abstract: front page image
(EN)The invention is directed to transfection reagents for the delivery of nucleic acids into neural cells, compositions including the reagents, methods of preparation of such reagents, methods of transfecting cells with such reagents, and uses thereof. In preferred embodiments the reagents comprise horseradish peroxidase and/or a polycarboxylic acid such as poly(acrylic acid) or poly(methacrylic acid).
(FR)L'invention concerne des réactifs de transfection pour l'apport d'acides nucléiques dans des cellules neurales, des compositions contenant ces réactifs, des procédés de préparation de tels réactifs, des méthodes de transfection de cellules avec ces réactifs, et leurs utilisations. Dans des modes de réalisation préférés, les réactifs comprennent de la péroxydase du raifort et/ou un acide polycarboxylique tel qu'un poly(acide acrylique) ou un poly(acide méthacrylique).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)