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1. (WO2012108635) COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE CONTAINING MIXED HERBAL EXTRACT OF CNIDIUM OFFICINALE ROOT AND RHEI UNDULATI RHIZOME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/108635    International Application No.:    PCT/KR2012/000718
Publication Date: 16.08.2012 International Filing Date: 31.01.2012
IPC:
A61K 36/234 (2006.01), A61K 36/708 (2006.01), A61P 11/06 (2006.01), A61P 11/00 (2006.01)
Applicants: WHANIN PHARMACEUTICAL CO., LTD. [KR/KR]; 84-1, Moonjung-dong, Songpa-gu Seoul 443-270 (KR) (For All Designated States Except US).
CHO, Yong Baik [KR/KR]; (KR) (For US Only).
KANG, Moon Kyu [KR/KR]; (KR) (For US Only).
JUNG, In Ho [KR/KR]; (KR) (For US Only).
HUR, Jong Hyun [KR/KR]; (KR) (For US Only).
KIM, Soon Han [KR/KR]; (KR) (For US Only).
JUNG, Kyoung Chul [KR/KR]; (KR) (For US Only).
LEE, Je Young [KR/KR]; (KR) (For US Only).
KIM, Seul Ki [KR/KR]; (KR) (For US Only).
LEE, Jee Young [KR/KR]; (KR) (For US Only).
YU, Byung Chul [KR/KR]; (KR) (For US Only).
HYON, Min-Kyong [KR/KR]; (KR) (For US Only)
Inventors: CHO, Yong Baik; (KR).
KANG, Moon Kyu; (KR).
JUNG, In Ho; (KR).
HUR, Jong Hyun; (KR).
KIM, Soon Han; (KR).
JUNG, Kyoung Chul; (KR).
LEE, Je Young; (KR).
KIM, Seul Ki; (KR).
LEE, Jee Young; (KR).
YU, Byung Chul; (KR).
HYON, Min-Kyong; (KR)
Agent: BAIK, Kyong Up; 5th Fl. Korea Development Bank Bldg., 946 Doonsan2-dong, Seo-gu Daejeon 302-828 (KR)
Priority Data:
10-2011-0012410 11.02.2011 KR
Title (EN) COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE CONTAINING MIXED HERBAL EXTRACT OF CNIDIUM OFFICINALE ROOT AND RHEI UNDULATI RHIZOME
(FR) COMPOSITION PERMETTANT DE PRÉVENIR OU DE TRAITER UNE MALADIE RESPIRATOIRE CONTENANT UN MÉLANGE D'EXTRAITS D'HERBES CONSTITUÉ DE RACINE DE CNIDIUM OFFICINALE ET DE RIZHOME DE RHEI UNDULATI
(KO) 천궁 및 종대황의 혼합 생약 추출물을 함유하는 호흡기 질환의 예방 또는 치료용 조성물
Abstract: front page image
(EN)The present invention relates to a composition for preventing or treating a respiratory disease, the composition containing an active ingredient in the form of a mixed herbal extract of Cnidium officinale root (Cnidii Rhizoma) and Rhei undulati (Undulatum Rhubarb) rhizome, and the present invention also relates to a production method therefor. The mixed herbal extract of Cnidium officinale root and Rhei undulati rhizome has an outstanding 5-lipoxygenase suppressing activity, airway constriction suppressing activity, airway inflammation suppressing action, ear-swelling anti-inflammatory effect and antitussive and phlegm loosening activity, and has been confirmed to be useful in preventing or treating respiratory diseases including asthma, chronic obstructive pulmonary disease, acute and chronic bronchitis, allergic rhinitis, cough, expectoration, acute lower respiratory infections (bronchitis and bronchiolitis), and acute upper respiratory infections such as pharyngitis, tonsillitis and laryngitis.
(FR)La présente invention concerne une composition pour prévenir ou traiter une maladie respiratoire, laquelle composition contient un principe actif sous la forme d'un mélange d'extraits d'herbes constitué de racine de Cnidium officinale (Rhizome Cnidii) et de rizhome de Rhei undulati (R.Undulatum). La présente invention concerne également un procédé de production correspondant. Le mélange d'extraits d'herbes constitué de racine de Cnidium officinale et de rizhome de Rhei undulati présente une activité exceptionnelle en termes de suppression de la 5-lipoxygénase, de suppression de la constriction des voies respiratoires, d'action anti-inflammatoire sur les voies respiratoires, d'effet anti-inflammatoire pour la tuméfaction de l'oreille ainsi qu'un effet anti-tussif et un effet mucolytique. En outre, ce mélange se révèle utile pour prévenir ou traiter des maladies respiratoires parmi lesquelles l'asthme, une maladie pulmonaire obstructive chronique, une bronchite chronique aiguë, une rhinite allergique, la toux, l'expectoration, des infections aiguës des voies respiratoires basses (bronchites et bronchiolites), et des infections aiguës des voies respiratoires hautes telles que la pharyngite, l'amygdalite et la laryngite.
(KO)본 발명은 천궁(Cnidii Rhizoma) 및 종대황(Undulatum Rhubarb)의 혼합 생약 추출물을 유효성분으로 함유하는 호흡기 질환의 예방 또는 치료용 조성물 및 이의 제조방법에 관한 것으로, 상기 천궁 및 종대황의 혼합 생약 추출물은 5-리폭시게나제 억제 활성, 기도수축억제 활성, 기도염증 억제 작용, 귀부종 소염 효과, 진해 및 거담 활성이 우수하여, 천식, 만성폐쇄성폐질환, 급만성기관지염, 알레르기 비염, 기침, 가래, 급성하기도 감염증(기관지염 및 세기관지염), 인후염, 편도염, 후두염과 같은 급성상기도감염증 등의 호흡기질환의 예방 또는 치료에 유용한 것으로 확인된다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)