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1. WO2012107708 - ADMINISTRATION REGIME FOR NITROCATECHOLS

Publication Number WO/2012/107708
Publication Date 16.08.2012
International Application No. PCT/GB2011/052056
International Filing Date 21.10.2011
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
4439
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
14
for treating abnormal movements, e.g. chorea, dyskinesia
16
Anti-Parkinson drugs
A61K 31/4439 (2006.01)
A61P 25/00 (2006.01)
A61P 25/16 (2006.01)
CPC
A61K 2121/00
A61K 31/165
A61K 31/198
A61K 31/4439
A61K 45/06
C07D 413/12
Applicants
  • BIAL - PORTELA & CA, S.A. [PT/PT]; A Av. da Siderurgia Nacional P-4745-457 S. Mamede do Coronado, PT (AllExceptUS)
  • SOARES DA SILVA, Patricio Manuel Vieira Araujo [PT/PT]; PT (UsOnly)
  • NUNES, Teresa Lucia Silva Pereira [PT/PT]; PT (UsOnly)
  • WRIGHT, Lyndon Christopher [GB/PT]; PT (UsOnly)
  • PALMA, Pedro Nuno Leal [PT/PT]; PT (UsOnly)
  • LEARMONTH, David Alexander [GB/PT]; PT (UsOnly)
Inventors
  • SOARES DA SILVA, Patricio Manuel Vieira Araujo; PT
  • NUNES, Teresa Lucia Silva Pereira; PT
  • WRIGHT, Lyndon Christopher; PT
  • PALMA, Pedro Nuno Leal; PT
  • LEARMONTH, David Alexander; PT
Agents
  • ELKINGTON AND FIFE LLP; Prospect House 8 Pembroke Road Sevenoaks Kent TN13 1XR, GB
Priority Data
61/441,98811.02.2011US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ADMINISTRATION REGIME FOR NITROCATECHOLS
(FR) RÉGIME D'ADMINISTRATION DE NITROCATÉCHOLS
Abstract
(EN)
A compound of formula (I) where R1, R2, X, Y, n, m, R3, R4, R5, R6 and R7 are as defined herein, for use in the prophylaxis or treatment of a central and peripheral nervous system disorder, wherein the compound of formula (I) is administered prior to sleep, before bedtime or at bedtime.
(FR)
L'invention concerne un composé de formule (I) dans laquelle R1, R2, X, Y, n, m, R3, R4, R5, R6 et R7 sont tels que définis ici, destinés à être utilisés dans la prophylaxie ou le traitement d'un trouble du système nerveux central et périphérique, le composé de formule (I) étant administré avant l'endormissement, avant le coucher ou au moment du coucher.
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