WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012107211) ANTI-ALPHA-V INTEGRIN ANTIBODY FOR THE TREATMENT OF PROSTATE CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/107211    International Application No.:    PCT/EP2012/000548
Publication Date: 16.08.2012 International Filing Date: 07.02.2012
IPC:
A61K 39/395 (2006.01), A61P 39/00 (2006.01), C07K 16/28 (2006.01), C07K 16/30 (2006.01)
Applicants: MERCK PATENT GMBH [DE/DE]; Frankfurter Strasse 250 64293 Darmstadt (DE) (For All Designated States Except US).
HOFFMANN, Axel [DE/DE]; (DE) (For US Only).
LANNERT, Heinrich [DE/DE]; (DE) (For US Only).
BRISCHWEIN, Klaus [DE/DE]; (DE) (For US Only).
PIPP, Frederic Christian [DE/DE]; (DE) (For US Only).
REINDL, Juergen [DE/DE]; (DE) (For US Only).
GROLL, Karin [DE/DE]; (DE) (For US Only).
ZUEHLSDORF, Michael [DE/DE]; (DE) (For US Only).
PFAFF, Otmar [DE/DE]; (DE) (For US Only).
RAAB, Sabine [DE/DE]; (DE) (For US Only).
DAU, Ulrike [DE/DE]; (DE) (For US Only).
DESTENAVES, Benoit [FR/FR]; (FR) (For US Only)
Inventors: HOFFMANN, Axel; (DE).
LANNERT, Heinrich; (DE).
BRISCHWEIN, Klaus; (DE).
PIPP, Frederic Christian; (DE).
REINDL, Juergen; (DE).
GROLL, Karin; (DE).
ZUEHLSDORF, Michael; (DE).
PFAFF, Otmar; (DE).
RAAB, Sabine; (DE).
DAU, Ulrike; (DE).
DESTENAVES, Benoit; (FR)
Priority Data:
11001135.0 11.02.2011 EP
Title (EN) ANTI-ALPHA-V INTEGRIN ANTIBODY FOR THE TREATMENT OF PROSTATE CANCER
(FR) ANTICORPS ANTI-ALPHA-V INTÉGRINE POUR LE TRAITEMENT DU CANCER DE LA PROSTATE
Abstract: front page image
(EN)The invention is directed to the treatment of prostate cancer by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from prostate cancer, especially castration- resistant prostate cancer (CRPC), optionally accompanied by lymph node and bone tissue metastases (mCRPC). In particular, the invention relates to the therapy of said patients by means of the anti-angiogenic antibody DI17E6 and structural mutants thereof.
(FR)L'invention concerne le traitement du cancer de la prostate au moyen d'anticorps. Avant tout, l'invention concerne l'administration d'un anticorps anti-(récepteur) alpha-V intégrine à des patients souffrant d'un cancer de la prostate, en particulier d'un cancer de la prostate résistant à la castration (CRPC), facultativement accompagné par des métastases des nœuds lymphatiques et du tissu osseux (mCRPC). En particulier, l'invention concerne la thérapie desdits patients au moyen d'un anticorps anti-angiogène DI17E6 et de mutants structuraux de celui-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)