WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012106490) MULTIVALENT VACCINES FOR RABIES VIRUS AND FILOVIRUSES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/106490    International Application No.:    PCT/US2012/023575
Publication Date: 09.08.2012 International Filing Date: 02.02.2012
IPC:
C12N 7/00 (2006.01), A61K 39/12 (2006.01), C12N 15/86 (2006.01), A61K 39/295 (2006.01)
Applicants: THE GOVERNMENT OF THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES [US/US]; Office of Technology Transfer 6011 Executive Boulevard Suite 325 Rockville, MD 20852 (US) (For All Designated States Except US).
BLANEY, Joseph, E. [US/US]; (US) (For US Only).
PARAGAS, Jason [US/US]; (US) (For US Only).
JAHRLING, Peter [US/US]; (US) (For US Only).
JOHNSON, Reed [US/US]; (US) (For US Only).
SCHNELL, Mathias [US/US]; (US) (For US Only)
Inventors: BLANEY, Joseph, E.; (US).
PARAGAS, Jason; (US).
JAHRLING, Peter; (US).
JOHNSON, Reed; (US).
SCHNELL, Mathias; (US)
Agent: CORLESS, Peter, F.; Edwards Wildman Palmer LLP P.O. Box 55874 Boston, MA 02205 (US)
Priority Data:
61/439,046 03.02.2011 US
Title (EN) MULTIVALENT VACCINES FOR RABIES VIRUS AND FILOVIRUSES
(FR) VACCINS MULTIVALENTS POUR LE VIRUS DE LA RAGE ET DES FILOVIRUS
Abstract: front page image
(EN)The present invention provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a filovirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a filovirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present invention provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one filovirus glycoprotein or an immunogenic fragment thereof, as well as pharmaceutical compostions comprising the vaccine vectors.
(FR)La présente invention concerne des méthodes et des compositions pour l'induction d'une réponse immunitaire qui confère une double protection contre des infections par l'un ou l'autre ou les deux parmi le virus de la rage et un filovirus, et/ou qui peuvent être thérapeutiquement utilisées pour une infection existante par le virus de la rage et/ou un filovirus pour traiter au moins un symptôme associé et/ou pour neutraliser ou éliminer les agents infectieux. En particulier, la présente invention concerne un vecteur recombinant viral de la rage comprenant une séquence nucléotidique codant au moins pour une glycoprotéine de filovirus ou un fragment immunogène de celle-ci, ainsi que des compositions pharmaceutiques comprenant les vecteurs de vaccin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)