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Machine translation
1. (WO2012106472) NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/106472    International Application No.:    PCT/US2012/023546
Publication Date: 09.08.2012 International Filing Date: 01.02.2012
IPC:
C07D 471/04 (2006.01), A61K 31/4375 (2006.01), A61P 9/10 (2006.01)
Applicants: FIBROGEN, INC. [US/US]; 409 Illinois Street San Francisco, California 94158 (US) (For All Designated States Except US).
NG, Danny [US/US]; (US) (For US Only).
AREND, Michael P. [DE/US]; (US) (For US Only).
FLIPPIN, Lee A. [US/US]; (US) (For US Only)
Inventors: NG, Danny; (US).
AREND, Michael P.; (US).
FLIPPIN, Lee A.; (US)
Agent: TANNER, Lorna L.; Foley & Lardner LLP 975 Page Mill Road Palo Alto, California 94304 (US)
Priority Data:
61/438,929 02.02.2011 US
Title (EN) NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE
(FR) DÉRIVÉS DE NAPHTHYRIDINE EN TANT QU'INHIBITEURS D'UN FACTEUR INDUCTIBLE PAR L'HYPOXIE
Abstract: front page image
(EN)The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
(FR)La présente invention concerne de nouveaux composés, procédés et nouvelles compositions aptes à inhiber l'activité enzymatique HIF hydroxylase, augmentant ainsi la stabilité et/ou l'activité d'un facteur inductible par l'hypoxie (HIF).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)